Aaron A Sasson

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This review describes the recent advances in the molecular events involved in pancreatic cancer initiation, progression, and metastasis. Additionally, the importance of deregulated cellular signaling elements as potential targets for developing novel therapeutic strategies against incurable forms of pancreatic cancer is reported. The emphasis is on the(More)
OBJECTIVE:The human MUC4 mucin plays an important role in the pathogenesis of pancreatic cancer. Recently, we have demonstrated that MUC4 expression in pancreatic tumor cells is regulated by interferon-γ (IFNγ) and by retinoic acid via transforming growth factor β 2 (TGFβ-2). In the present study, we established the pathobiological association of various(More)
A total of 41 consecutive cases of unstable lumbar and lower thoracic spine fractures or fracture dislocations were treated by the authors at the Soroka Medical Center, Beer-Sheva, Israel between 1988 and 1992, using the Dick Internal Fixator, for reduction of the deformity and fixation. Twenty-nine of the 41 cases, 19 males and 10 females with an average(More)
Computed tomography metrizamide myelography of the lumbar spine in the prone position is advocated for better visualisation of the thecal sac-disc annulus interface. This method allows a more precise diagnosis of disc herniation. Therefore, it is suggested that this technique should routinely be performed prone. In cases where suspended respiration in the(More)
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