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: The management of perioperative bleeding involves multiple assessments and strategies to ensure appropriate patient care. Initially, it is important to identify those patients with an increased risk of perioperative bleeding. Next, strategies should be employed to correct preoperative anaemia and to stabilise macrocirculation and microcirculation to(More)
The evaluation of tetracycline as a chemoprophylactic agent for cholera is described. Families of cholera patients were divided into 4 groups by strict rotation. The first group received multivitamin preparations and served as the control. The second received 1.0 g of tetracycline, divided into 4 doses, daily for 5 days, the third received 1.0 g of(More)
We aimed to validate the mathematical validity and accuracy of the respiratory components of the Nottingham Physiology Simulator (NPS), a computer simulation of physiological models. Subsequently, we aimed to assess the accuracy of the NPS in predicting the effects of a change in mechanical ventilation on patient arterial blood-gas tensions. The NPS was(More)
We conducted a postal survey of cardiac anaesthetists in the UK, to determine the extent of magnesium sulphate (MgSO4) use and the main indications for its administration. Questionnaires were sent to anaesthetists at 35 UK hospitals undertaking adult cardiac surgery. Responses were received from 24 hospitals (69%) totalling 124 individual responses.(More)
In a randomized, double-blind trial, we compared i.v. ondansetron 4 mg (control), i.v. ondansetron 4 mg and cyclizine 50 mg (combination) and i.v. saline 0.9% (placebo), given after induction of standardized anaesthesia, for the prevention of nausea and vomiting (PONV) after day-case gynaecological laparoscopic surgery. Compared with placebo, fewer patients(More)
STUDY OBJECTIVE To determine the effect of head position on success of tracheal intubation through a Laryngeal Mask Airway (LMA) using a gum elastic bougie. DESIGN Randomized, controlled study. SETTING Anesthesia and operating rooms of the University Hospital, Nottingham, UK. PATIENTS 20 patients scheduled to undergo routine elective surgery requiring(More)
The anaesthetic management of a 30-year-old pregnant quadriplegic patient with severe respiratory insufficiency undergoing Caesarean section is described. Quadriplegia and respiratory insufficiency pose potential problems for anaesthetists and these are discussed. In particular autonomic hyperreflexia may occur and this may be mistaken for pre-eclampsia.
In a retrospective study of bleeding patients in cardiac surgery, Cappabianca et al. [1] observed that the use of prothrombin complex concentrate (PCC) compared with fresh-frozen plasma (FFP) was associated with a higher risk of postoperative renal complications. In the un-adjusted comparison, acute kidney injury (AKI) incidence was significantly higher in(More)