Aakanksha Pant

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Beta-caryophyllene (BCP) is a natural bicyclic sesquiterpene and is a FDA approved food additive, found as an active ingredient in essential oils of numerous edible plants. It possesses a wide range of biological activities including anti-oxidant, anti-inflammatory, anti-cancerous and local anesthetic actions. We used the well established Caenorhabditis(More)
An Ayurvedic polyherbal extract (PHE) comprising six herbs viz. Berberis aristata, Cyperus rotundus, Cedrus deodara, Emblica officinalis, Terminalia chebula and Terminalia bellirica is mentioned as an effective anti-hyperglycemic agent in ‘Charaka Samhita’, the classical text of Ayurveda. Previously, antidiabetic drug metformin was found to elicit antiaging(More)
The use of herbs in the form of dietary supplements and medicine is fascinating the world, owing to their safety and protective effects against oxidative stress. The elevation in oxidative stress promotes aging and age related disorders. To this end, the authors evaluated in vivo antioxidant activity and anti-aging potential of Trachyspermum ammi L. (TA)(More)
Polysaccharide (PS) capsules are important virulence determinants for many bacterial pathogens. Bordetella pertussis, the agent of whooping cough, produces a surface associated microcapsule but its role in pertussis pathogenesis remained unknown. Here we showed that the B. pertussis capsule locus is expressed in vivo in murine lungs and that absence of the(More)
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