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If the distribution P is considered random and distributed according to , as it is in Bayesian inference, then the posterior distribution is the conditional distribution of P given the observations. The prior is, of course, a measure on some σ-field on and we must assume that the expressions in the display are well defined. In particular, we assume that the… (More)

We study the rates of convergence of the maximum likelihood estimator (MLE) and posterior distribution in density estimation problems, where the densities are location or location-scale mixtures of normal distributions with the scale parameter lying between two positive numbers. The true density is also assumed to lie in this class with the true mixing… (More)

- Kees Jong, Elena Marchiori, Gerrit Meijer, Aad van der Vaart, Bauke Ylstra
- Bioinformatics
- 2004

SUMMARY
We describe a tool, called aCGH-Smooth, for the automated identification of breakpoints and smoothing of microarray comparative genomic hybridization (array CGH) data. aCGH-Smooth is written in visual C++, has a user-friendly interface including a visualization of the results and user-defined parameters adapting the performance of data smoothing and… (More)

- B . T . KNAPIK, Aad van der Vaart, Jan van Zanten
- 2011

The posterior distribution in a nonparametric inverse problem is shown to contract to the true parameter at a rate that depends on the smoothness of the parameter, and the smoothness and scale of the prior. Correct combinations of these characteristics lead to the minimax rate. The frequentist coverage of credible sets is shown to depend on the combination… (More)

- Kees Jong, Elena Marchiori, Aad van der Vaart
- EvoWorkshops
- 2004

In this paper we analyze two proteomic pattern datasets containing measurements from ovarian and prostate cancer samples. In particular, a linear and a quadratic support vector machine (SVM) are applied to the data for distinguishing between cancer and benign status. On the ovarian dataset SVM gives excellent results, while the prostate dataset seems to be… (More)

Abstract: We consider nonparametric Bayesian estimation of a probability density p based on a random sample of size n from this density using a hierarchical prior. The prior consists, for instance, of prior weights on the regularity of the unknown density combined with priors that are appropriate given that the density has this regularity. More generally,… (More)

We consider the asymptotic behavior of posterior distributions if the model is misspecified. Given a prior distribution and a random sample from a distribution P0, which may not be in the support of the prior, we show that the posterior concentrates its mass near the points in the support of the prior that minimize the Kullback–Leibler divergence with… (More)

We consider the problem of testing monotonicity of the regression function in a nonparametric regression model. We introduce test statistics that are functionals of a certain natural U-process. We study the limiting distribution of these test statistics through strong approximation methods and the extreme value theory for Gaussian processes. We show that… (More)

- Kees Jong, Elena Marchiori, Michèle Sebag, Aad van der Vaart
- 2004 Symposium on Computational Intelligence in…
- 2004

This work introduces novel methods for feature selection (FS) based on support vector machines (SVM). The methods combine feature subsets produced by a variant of SVM-RFE, a popular feature ranking/selection algorithm based on SVM. Two combination strategies are proposed: union of features occurring frequently, and ensemble of classifiers built on single… (More)