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With industrial revolution came idea of " two spheres " Because it wasn't paid, women's housework was devalued A majority of women are now in the labor force However, in two-wage earner couples, women continue to do more housework than men Wives (1995): 19.4 hours per week; husbands: 10.4 hours When women marry their housework goes up Non-married women(More)
From a social capital theoretical perspective, deficiencies in access to mainstream ties and institutions explain persistent joblessness among the black urban poor. Little problematized, however, is the extent to which access leads to mobilization and the social context within which social capital activation occurs. Employing in-depth interviews of 105(More)
The Family and Medical Leave Act requires employers to provide job-protected leave, but little is known about how these leave rights operate in practice or how they interact with other normative systems to construct the meaning of leave. Drawing on interviews with workers who negotiated contested leaves, this study examines how social institutions influence(More)
Lambda repressors bind cooperatively to adjacent pairs of operator sites. Here we show that repressors bind cooperatively to pairs of operator sites whose centers have been separated by five or six turns of the helix. No cooperativity is observed when the centers of these sites are on opposite sides of the DNA helix. Cooperativity depends upon the same part(More)
It has been shown by Hochschild and Ptashne that lambda repressors bind cooperatively to operator sites separated by five or six turns of the helix. Cooperative binding is not observed if the sites are separated by a nonintegral number of turns, unless a four-nucleotide gap is introduced into one of the strands between the two sites. These and other facts(More)
It has been suggested that the lambda repressor stimulates transcription of its own gene by binding to the lambda operator and contacting RNA polymerase bound to the adjacent promoter. We describe three different mutants (called pc) of the lambda phage repressor that are specifically deficient in the positive control function. We show that the amino acid(More)
Interactions between transcription factors bound to separate operator sites commonly play an important role in gene regulation by mediating cooperative binding to the DNA. However, few detailed structural models for understanding the molecular basis of such cooperativity are available. The c1 repressor of bacteriophage lambda is a classic example of a(More)
a 34-year-old mother of five, was a college-educated schoolteacher and travel agent in the Philippines before migrating to the United States to work as a housekeeper for a wealthy Beverly Hills family and as a nanny for their two-year-old son. As Vicky explained in an interview with Rhacel Parreñas, My children … were saddened by my departure. Even until(More)
Although lambda repressor and lambda Cro bind to the same six operators on the phage chromosome, the fine specificities of the two proteins differ: repressor binds more tightly to OR1 than to OR3, and vice versa for Cro. In this paper, we change base pairs in the operators and amino acids in the proteins to analyze the basis for these preferences. We find(More)