AM Viloria-Petit

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Inhibitors of epidermal growth factor receptor (EGFR) signaling are among the novel drugs showing great promise for cancer treatment in the clinic. However, the possibility of acquired resistance to such drugs because of tumor cell genetic instabilities has not yet been explored. Here we report the experimental derivation and properties of such cell(More)
Interleukin (IL)-25, a cytokine active in inflammatory processes and production of proinflammatory cytokines, is secreted by mammary epithelial non-malignant cells and induces apoptosis in tumour cells by differential expression of its receptor IL-17RB, highly expressed in malignant cells and lower expressed in non-malignant epithelial cells. It is known(More)
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