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It was shown by Soodak and Cerecedo (2) that oxythiamine was toxic to mice maintained on suboptimal levels of thiamine. Jones et al. (3) have used oxythiamine as a means of producing a controlled deficiency state in mice with a view of studying the effect of thiamine deficiency on the Lansing strain of poliomyelitis virus. That oxythiamine acts as a(More)
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