AG Unnikrishnan

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This paper reviews the incidence, pathogenetic mechanisms and management strategies of diabetes mellitus in patients with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). It classifies patients based on the aetiopathogenetic mechanisms, and proposes rational methods of management of the condition, based on aetiopathogenesis(More)
Type 1 diabetes (T1D) is the most common form of diabetes in children in Western countries. There have been no large studies of childhood diabetes from India. We undertook the MEDI study (Multicenter Survey of Early Onset Diabetes in India) to assess the proportion of various subtypes of diabetes among the young subjects presenting to the endocrinology(More)
CLINICAL QUESTION Which antidiabetic drugs provide optimal weight control in patients with type 2 diabetes? RESULTS Metformin reduces weight gain, and may cause weight loss, when given alone or in combination with other drugs. Pioglitazone and rosiglitazone use is associated with weight gain. Use of the glucagon-like peptide-1 (GLP-1) analogs, liraglutide(More)
Aortic dissection is a rare and life-threatening event. While pain is the most common symptom of aortic dissection, it may be absent in ten percent of patients and present with a myriad of symptoms suggestive of a diverse range of other conditions. A high index of clinical suspicion is mandatory for the accurate and rapid diagnosis of aortic dissection. We(More)
Introduction A thyroid nodule is a discrete lesion within the thyroid gland that is palpably or radiologically distinct from the surrounding thyroid parenchyma.1 Nodular diseases of the thyroid are very common, seen in about 8.5 % of the population.2 They are commoner amongst women. Thyroid cancer is relatively rarerthe incidence is 8.7 per 100000 people(More)
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