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The pattern of cognitive deficits and their time-dependent recovery were investigated in a cohort of 49 male alcohol-dependent patients using a repeated measurement design with 49 healthy male controls matched for age, education, and marital status. We combined parts of the Halstead Reitan Battery and the Wechsler Memory Scale with tests that are widely(More)
The pathogenic relationship between the presence of Y chromosomal microdeletions and male infertility is unclear. Nevertheless, a causal relationship is thought to be probable when loci are shown to be deleted in infertile males but are present in fertile males. Polymerase chain reaction (PCR) analysis of the Y chromosome is now routinely performed in the(More)
BACKGROUND Recently we showed that antibodies to myelin oligodendrocyte glycoprotein (MOG) can be found in aquaporin-4 (AQP4)-immunoglobulin (IgG) seronegative pediatric and adult patients with definite and high-risk neuromyelitis optica (NMO). OBJECTIVE The purpose of this study was to describe the clinical characteristics and temporal dynamics of(More)
We aimed to determine long-term disability and quality of life in patients with Guillain-Barré syndrome (GBS) who required mechanical ventilation (MV) in the acute phase. Our retrospective cohort study included 110 GBS patients admitted to an intensive care unit and requiring MV (01/1999-08/2010) in nine German tertiary academic medical centers. Outcome was(More)
Although it is well known that cigarette smoking is a risk factor for the development of atherosclerosis, facts have been scarce concerning mechanisms for the effects of smoke on the blood vessel wall. New findings show that endothelial cells are activated by substances found in smoke, so that leukocytes adhere to and interact with them. Among such(More)
The effects of antihypertensive drug therapy were assessed in 8,459 patients (2,801 men and 5,658 women) from the hypertension register of the North Karelia Project in 1978-1979. Fifty-two per cent of the men and 56% of the women were taking one drug only. The most common drugs used were diuretics and beta-blockers. Women were on diuretics more often than(More)
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