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Chemistry of the natural cyclosporin metabolites.
[Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity].
Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (LINK ex PERS.) Rifai, with a remarkable immunosuppressive activity Two antifungal metabolites, cyclosporins A and C, wereExpand
Cyclosporins, fungal metabolites with immunosuppressive activities.
Publisher Summary This chapter discusses cyclosporins, fungal metabolites with immunosuppressive activities. The fungal metabolite, cyclosporin A [1,2], exerts a powerful immunosuppressive activityExpand
Tetronomycin, a novel polyether of unusual structure.
Tetronomycin, C34H50O8, isolated from a strain of Streptomyces sp. nov. represents a novel polycyclic ionophore polyether. The crystal structure and absolute configuration were established by X-rayExpand
Septamycin, a polyether antibiotic. Taxonomy, fermentation, isolation and characterization.
Septamycin is a metal complexing polyether antibiotic produced by a strain of Streptomyces hygroscopicus NRRL 5678. The metabolite, a monocarboxylic acid, was isolated as the sodium salt C48H81NaO16.Expand
Noboritomycins A and B, new polyether antibiotics.
Noboritomycins A and B, two new polycyclic ionophoric polyethers were isolated from a strain of Streptomyces noboritoensis. The crystal structure and absolute configuration of noboritomycin A wereExpand
From podophyllotoxin glucoside to etoposide.
[The separation of acyl protection groups in alkali-sensitive glucosides. Synthesis of podophyllotoxin-beta-D-glucoside].
The synthesis of podophyllotoxin-β-D-glucoside (III), an antimitotic lignan compound isolated from Podophyllum species, is reported. Reaction of podophyllotoxin (I) withExpand
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