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Mapping the Onset of Psychosis: The Comprehensive Assessment of At-Risk Mental States
The CAARMS instrument provides a useful platform for monitoring sub threshold psychotic symptoms for worsening into full-threshold psychotic disorder and has good to excellent reliability.
Psychosis prediction: 12-month follow up of a high-risk (“prodromal”) group
Neuroanatomical abnormalities before and after onset of psychosis: a cross-sectional and longitudinal MRI comparison
Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subthreshold symptoms.
More specific pharmacotherapy and psychotherapy reduces the risk of early transition to psychosis in young people at ultra-high risk, although their relative contributions could not be determined.
The psychosis high-risk state: a comprehensive state-of-the-art review.
The relatively new field of HR research in psychosis has the potential to shed light on the development of major psychotic disorders and to alter their course and provides a rationale for service provision to those in need of help who could not previously access it.
Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features
Cognitive functioning in prodromal psychosis: a meta-analysis.
The HR state for psychosis is associated with significant and widespread impairments in neurocognitive functioning and social cognition, and subsequent transition to psychosis is particularly associated with deficits in verbal fluency and memory functioning.
The prodromal phase of first-episode psychosis: past and current conceptualizations.
This article proposes an alternative model for conceptualizing prodromal changes (the hybrid/interactive model) and discusses the different ways to view this phase of first-episode psychosis.
Prediction of psychosis
It is demonstrated that it is possible to identify individuals with a high likelihood of onset of psychosis within a brief follow-up period, which lays the foundation for early treatment in an attempt to prevent, delay or minimise the severity of first onset of schizophrenia.