• Publications
  • Influence
Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential.
TLDR
Retention of 62Cu-ATSM was studied serially in perfused rat hearts under conditions of normoxia, hypoxia and reoxygenation, and retention was increased markedly under hypoxic conditions, with inversely correlated with accumulation of 201Tl, a relative myocardial blood flow marker. Expand
Determination of amphetamine and methamphetamine in human hair by headspace solid-phase microextraction and gas chromatography with nitrogen-phosphorus detection.
TLDR
By using this method, AP and MA in human hair could be analyzed simply and rapidly without any interference from coexisting substances and could be applied to the analysis of an abuser's hair sample. Expand
Deferoxamine, a promising bifunctional chelating agent for labeling proteins with gallium: Ga-67 DF-HSA: concise communication.
TLDR
High stability of the Ga-67 DF-HSA was observed both in vitro and in vivo, and the excellent pharmacological and physiological properties were assessed by plasma clearance and plasma volume measurements in normal volunteers. Expand
Myocardial accumulation of iodinated beta-methyl-branched fatty acid analogue, iodine-125-15-(p-iodophenyl)-3-(R,S)methylpentadecanoic acid (BMIPP), in relation to ATP concentration.
TLDR
Following treatment with DNP, decreases in myocardial BMIPP accumulation correlated well with those of ATP, while 201Tl-Cl showed slightly increased accumulation in the myocardium, suggesting that in some diseases, BMIPP may be useful in evaluating myocardian ATP levels. Expand
The importance of glucose transport activity as the rate-limiting step of 2-deoxyglucose uptake in tumor cells in vitro.
TLDR
Cultured tumor cells showed higher DG uptake and 3-O-MG transport than the human fibroblast cells, which suggests that DG uptake of cultured tumor cells is governed by GLUT expression, which may be a distinct characteristic of the neoplastic process. Expand
Reassessment of diethylenetriaminepentaacetic acid (DTPA) as a chelating agent for indium-111 labeling of polypeptides using a newly synthesized monoreactive DTPA derivative.
TLDR
It is indicated that MDTPA and its precursor, the tetra-tert-butyl derivative of DTPA, would be useful BCAs for 111In radiolabeling of polypeptides that have rapid blood clearance with high specific activities. Expand
Effect of DTPA conjugation on the antigen binding activity and biodistribution of monoclonal antibodies against alpha-fetoprotein.
TLDR
The number of DTPA molecules incorporated per Ab molecule markedly influenced the in vivo biodistribution as well as the in vitro antigen binding activity, and the Scatchard plot analysis demonstrated that the maximum binding capacity rather than the affinity constant was affected. Expand
A new zinc-62/copper-62 generator as a copper-62 source for PET radiopharmaceuticals.
TLDR
Copper in glycine solution showed rapid complex formation with dithiosemicarbazone, which is one of the established Cu-binding agents for bifunctional chelating radiopharmaceuticals. Expand
A biological method to evaluate bifunctional chelating agents to label antibodies with metallic radionuclides.
TLDR
The present method portrays a highly useful model to pursue the fate of radiolabeled metabolites in the liver using 1-isothiocyanatobenzyl)ethylenediaminetetraacetic acid (SCN-Bz-EDTA) as a model. Expand
A strategy for the study of cerebral amino acid transport using iodine-123-labeled amino acid radiopharmaceutical: 3-iodo-alpha-methyl-L-tyrosine.
TLDR
123I-L-AMT appears to be a useful radiopharmaceutical for the selective measurement of cerebral amino acid transport, both operating across the blood-brain barrier and cell membranes of the brain. Expand
...
1
2
3
4
5
...