• Publications
  • Influence
Bacterial colonization of distal airways in healthy subjects and chronic lung disease: a bronchoscopic study.
In contrast to the healthy population, distal airway bacterial colonization may occur in patients with chronic lung diseases, who often have altered pulmonary defences. However, the informationExpand
  • 279
  • 16
[Bronchoalveolar lavage].
  • 275
  • 12
Bacterial colonisation in patients with bronchiectasis: microbiological pattern and risk factors
Background: A study was undertaken to investigate the incidence, diagnostic yield of non-invasive and bronchoscopic techniques, and risk factors of airway colonisation in patients with bronchiectasisExpand
  • 272
  • 10
Bronchial inflammation and colonization in patients with clinically stable bronchiectasis.
To evaluate the bronchial inflammatory response and its relationship to bacterial colonization in bronchiectasis, we performed a bronchoalveolar lavage (BAL) in 49 patients in stable clinicalExpand
  • 222
  • 9
Validation of different techniques for the diagnosis of ventilator-associated pneumonia. Comparison with immediate postmortem pulmonary biopsy.
To assess the accuracy of clinical parameters for the diagnosis of ventilator-associated (VA) pneumonia, as well as the diagnostic value of several invasive techniques, such as protected specimenExpand
  • 246
  • 8
Expression of glucocorticoid receptor alpha- and beta-isoforms in human cells and tissues.
Alternative splicing of the human glucocorticoid receptor (GR) primary transcript generates two protein isoforms: GR-alpha and GR-beta. We investigated the expression of both GR isoforms in healthyExpand
  • 96
  • 8
Etiology and microbial patterns of pulmonary infiltrates in patients with orthotopic liver transplantation.
STUDY OBJECTIVE To evaluate the etiology and microbial patterns of pulmonary infiltrates in liver transplant patients using a bronchoscopic diagnostic approach and the impact of diagnostic results onExpand
  • 68
  • 7
Cyclooxygenase-2 mRNA is downexpressed in nasal polyps from aspirin-sensitive asthmatics.
Exogenous prostaglandin E2 (PGE2) given by inhalation almost completely abrogates aspirin-induced asthma and the accompanying increase in cysteinyl-leukotrienes production. Cyclooxygenase (COX) mayExpand
  • 225
  • 6
Transforming Growth Factor-β1 Gene Polymorphisms Are Associated with Disease Progression in Idiopathic Pulmonary Fibrosis
Transforming growth factor-β1 (TGF-β1) is a cytokine that plays a key role in the development of idiopathic pulmonary fibrosis. There have been reports on the presence of two genetic polymorphisms inExpand
  • 151
  • 6
Cytokine expression in severe pneumonia: a bronchoalveolar lavage study.
OBJECTIVE To assess the cytokine expression (tumor necrosis factor-alpha [TNF-alpha], interleukin [IL]-1beta, and IL-6) in severe pneumonia, both locally (in the lungs) and systemically (in blood).Expand
  • 161
  • 6