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DSulfatase-1 fine-tunes Hedgehog patterning activity through a novel regulatory feedback loop.
Sulfs are secreted sulfatases that catalyse removal of sulfate from Heparan Sulfate Proteoglycans (HSPGs) in the extracellular space. These enzymes are well known to regulate a number of crucial… Expand
Robustness of positional specification by the Hedgehog morphogen gradient.
Spatial gradients of Hedgehog signalling play a central role in many patterning events during animal development, regulating cell fate determination and tissue growth in a variety of tissues and… Expand
Network behavior-analysis systems with the use of learning set and decision rules based on distance
- Artur Sierszen, Łukasz Sturgulewski, Mary Élise Dubel, Tomasz Marciniak, Alexandre Wojcinski
- Computer Science
Endothelial cell-derived Indian Hedgehog targets multipotent perivascular cells in the adult choroid and prevents retinal damage