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Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.
The polymerase chain reaction is used to amplify homologous segments of mtDNA from more than 100 animal species, including mammals, birds, amphibians, fishes, and some invertebrates, and the unexpectedly wide taxonomic utility of these primers offers opportunities for phylogenetic and population research. Expand
Rapid evolution of animal mitochondrial DNA.
The rate of evolution of the mitochondrial genome appears to exceed that of the single-copy fraction of the nuclear genome by a factor of about 10 and is likely to be an extremely useful molecule to employ for high-resolution analysis of the evolutionary process. Expand
Evolution of the cytochrome b gene of mammals.
Comparisons of these cytochrome b sequences support current structure-function models for this membrane-spanning protein, which suggests that the outer surface which includes the Qo redox center is more constrained than the remainder of the molecule, namely, the transmembrane segments and the surface that protrudes into the mitochondrial matrix. Expand
African populations and the evolution of human mitochondrial DNA.
The African origin hypothesis of human mtDNA evolution is supported by two statistical tests and two hypervariable segments of mtDNA were sequenced from 189 people of diverse geographic origin, including 121 native Africans. Expand
Evolution at two levels in humans and chimpanzees.
Mitochondrial DNA sequences in single hairs from a southern African population.
Evidence of geographic structuring of the mitochondrial diversity in Africa, together with knowledge of the rate of accumulation of base changes in human mtDNA, implies that the average rate at which female lineages have moved their home bases during hunter-gatherer times could be as low as 13 meters per year. Expand
SSCP is not so difficult: the application and utility of single‐stranded conformation polymorphism in evolutionary biology and molecular ecology
SSCP (single‐stranded conformation polymorphism) offers a sensitive but inexpensive, rapid, and convenient method for determining which DNA samples in a set differ in sequence, so that only an informative subset need be sequenced. Expand
Immunological Time Scale for Hominid Evolution
The studies with the quantitative micro-complement fixation method confirm the observation that apes and man have a more recent common ancestry than is usually supposed and lead to the suggestion that man and Old World monkeys last shared a common ancestor 30 million years ago. Expand
Branching pattern in the evolutionary tree for human mitochondrial DNA.
Eighty-eight types of mitochondrial DNA were found by sequencing the most variable part of the control region from 117 Caucasians, implying that the probability of survival of new lineages has undergone dramatic changes, probably due to population expansion. Expand
Mitochondrial resolution of a deep branch in the genealogical tree for perching birds
The mitochondrial tree shows broad concordance with that based on hybridization of nuclear DNA; however, parsimony and maximum likelihood methods suggest a close kinship between thrushes and Australian babblers, in agreement with the traditional morphological classification. Expand