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A longitudinal, population-based, cohort study of childhood asthma followed to adulthood.
BACKGROUND The outcome of childhood asthma in adults has been described in high-risk cohorts, but few population-based studies have reported the risk factors for persistence and relapse. METHODS WeExpand
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Something old, something new, something borrowed, something blue: a framework for the marriage of health econometrics and cost-effectiveness analysis.
Economic evaluation is often seen as a branch of health economics divorced from mainstream econometric techniques. Instead, it is perceived as relying on statistical methods for clinical trials.Expand
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Objective To define the strengths and weaknesses of existing research on the natural history of cervical squamous intraepithelial lesions (SIL) and to estimate rates of progression and regressionExpand
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Cancer care workers in Ontario: prevalence of burnout, job stress and job satisfaction.
BACKGROUND Cancer Care Ontario's Systemic Therapy Task Force recently reviewed the medical oncology system in the province. There has been growing concern about anecdotal reports of burnout, highExpand
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Expected value of information and decision making in HTA.
Decision makers within a jurisdiction facing evidence of positive but uncertain incremental net benefit of a new health care intervention have viable options where no further evidence is anticipatedExpand
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Long-term relation between breastfeeding and development of atopy and asthma in children and young adults: a longitudinal study
BACKGROUND Breastfeeding is widely advocated to reduce risk of atopy and asthma, but the evidence for such an effect is conflicting. We aimed to assess long-term outcomes of asthma and atopy relatedExpand
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Regression methods for covariate adjustment and subgroup analysis for non-censored cost-effectiveness data.
The current interest in undertaking cost-effectiveness analyses alongside clinical trials has lead to the increasing availability of patient-level data on both the costs and effectiveness ofExpand
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Randomized Clinical Trial of Breast Irradiation Following Lumpectomy and Axillary Dissection for Node-Negative Breast Cancer: an Update
Background: Breast-conservation surgery is now commonly used to treat breast cancer. Postoperative breast irradiation reduces cancer recurrence in the breast. There is still controversy concerningExpand
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Statistical Analysis of Cost-Effectiveness Data
Preface. 1. Concepts. 1.1 Introduction. 1.2 Cost-effectiveness data and the parameters of interest. 1.3 The cost-effectiveness plane, the ICER and INB. 1.4 Outline. 2. Parameter Estimation forExpand
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