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Biochemistry of tropoelastin.
Elastic fibres are an important component of the extracellular matrix and are made of two major components : the more abundant cross-linked elastic protein elastin and the multi-componentExpand
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Electrospun protein fibers as matrices for tissue engineering.
Electrospinning has recently emerged as a leading technique for generating biomimetic scaffolds made of synthetic and natural polymers for tissue engineering applications. In this study, we comparedExpand
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Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells
Surprisingly little is known about the effects of the physical microenvironment on hemopoietic stem and progenitor cells. To explore the physical effects of matrix elasticity on well-characterizedExpand
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Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins.
P-Glycoproteins are transmembrane proteins associated with acquired multidrug resistance in mammalian cells and some protozoan parasites by a process of active drug export. P-glycoproteins containExpand
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A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties.
Small-diameter synthetic vascular graft materials fail to match the patency of human tissue conduits used in vascular bypass surgery. The foreign surface retards endothelialization and is highlyExpand
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Coacervation of tropoelastin.
The coacervation of tropoelastin represents the first major stage of elastic fiber assembly. The process has been modeled in vitro by numerous studies, initially with mixtures of solubilized elastin,Expand
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Synthetic elastin hydrogels derived from massive elastic assemblies of self-organized human protein monomers.
A key objective of bioengineering is the development of new scaffolding biomaterials with appropriate mechanical and biological properties such as strength, elasticity and biocompatibility that mimicExpand
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Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity
Elastin enables the reversible deformation of elastic tissues and can withstand decades of repetitive forces. Tropoelastin is the soluble precursor to elastin, the main elastic protein found inExpand
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Structural disorder and dynamics of elastin.
Elastin is a self-assembling, extracellular-matrix protein that is the major provider of tissue elasticity. Expand
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Cell Adhesion to Tropoelastin Is Mediated via the C-terminal GRKRK Motif and Integrin αVβ3*
Elastin fibers are predominantly composed of the secreted monomer tropoelastin. This protein assembly confers elasticity to all vertebrate elastic tissues including arteries, lung, skin, vocal folds,Expand
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