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Low‐field MRI: An MR physics perspective
The current state‐of‐the‐art of low‐field systems (defined as 0.25–1T), both with respect to its low cost, low foot‐print, and subject accessibility and how low field could potentially benefit from many of the developments that have occurred in higher‐field MRI are described.
Origin and reduction of motion and f0 artifacts in high resolution T2*-weighted magnetic resonance imaging: Application in Alzheimer's disease patients
Simulations of high permittivity materials for 7 T neuroimaging and evaluation of a new barium titanate‐based dielectric
A new material (barium titanate, relative permittivity ∼150) is used to produce thin dielectric pads which can easily be placed within a standard receive head array, and experimental measurements of transmit sensitivities, as well as acquisition of T2‐ and T 2* ‐weighted images show the promise of this approach.
Microstructural organization of axons in the human corpus callosum quantified by diffusion-weighted magnetic resonance spectroscopy of N-acetylaspartate and post-mortem histology
- I. Ronen, M. Budde, E. Ercan, J. Annese, A. Techawiboonwong, A. Webb
- BiologyBrain Structure and Function
- 1 September 2014
The notion that microscopic axonal misalignment is a dominant microstructural property in white matter tracts and has a strong impact on the evaluation of tissue microstructure using diffusion information, and should therefore be taken into consideration in the Evaluation of white matter microst structure is supported.
Differences in apparent diffusion coefficients of brain metabolites between grey and white matter in the human brain measured at 7 T
ADCs in grey matter were consistently lower than in white matter, and differences can probably be attributed to different compartmentalization as well as to the differential impact of diffusion time on ADC of different molecules under conditions of restricted diffusion.
Quantitative assessment of the effects of high‐permittivity pads in 7 Tesla MRI of the brain
Results in this article show that the use of high‐permittivity materials does not increase the intercoil coupling for a phased array receive coil, does not have any detrimental effects on the B0 homogeneity within the brain, and does not affect the specific absorption rate distribution within the head.
Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington’s disease provides in vivo evidence for impaired energy metabolism
- S. V. D. van den Bogaard, E. Dumas, J. van der Grond
- Biology, MedicineJournal of Neurology
- 26 May 2011
The lower concentrations of NAA and creatine in the caudate nucleus and putamen of early manifest HD suggest deficits in neuronal integrity and energy metabolism and could support the excitotoxicity theory.
New criterion to aid manual and automatic selection of the arterial input function in dynamic susceptibility contrast MRI
- E. J. Bleeker, M. V. van Osch, A. Connelly, M. van Buchem, A. Webb, F. Calamante
- BiologyMagnetic resonance in medicine
- 1 February 2011
A new criterion is proposed that detects shape errors based on tracer kinetic principles for computing cerebral blood volume using the ratio of the steady‐state value to the area‐under‐the‐curve of the first passage, which should result in an equal value for tissue and arterial responses.
Subject tolerance of 7 T MRI examinations
- M. Versluis, W. Teeuwisse, H. Kan, M. Buchem, A. Webb, M. Osch
- MedicineJournal of magnetic resonance imaging : JMRI
- 1 September 2013
To determine the subjective experiences and the sources of discomfort for subjects undergoing 7 T magnetic resonance imaging (MRI) examinations on a whole‐body 7 T system in a hospital setting, a large number of subjects reported experiencing discomfort.