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Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations
TLDR
AIP IHC, followed by genetic counseling and possible AIP mutation analysis in IHC-negative cases, appears feasible in identification of PAP, a procedure similar to the diagnostics of the Lynch syndrome. Expand
Electron microscopy methods and protocols
  • A. Wąsik
  • Medicine
  • Acta crystallographica. Section D, Biological…
  • 2000
TLDR
The readers have in their hands an excellent handbook providing description of the newest technologies in electron transmission microscopy (TEM) and scanning electron microscopy(SEM) with mass spec-trometry (MS), as well as the precise preparative procedures. Expand
Agglutinated loricae of some Baltic and Antarctic Tintinnina species (Ciliophora)
TLDR
The results suggest that certain diatoms are actively selected and agglutinated by particular tintinnid species. Expand
Aryl hydrocarbon receptor interacting protein (AIP) gene mutation analysis in children and adolescents with sporadic pituitary adenomas
TLDR
The aim of the study was to examine the proportion of germline AIP mutations in apparently sporadic paediatric pituitary adenomas. Expand
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
TLDR
It is suggested that DMLs combining 5-HT6R antagonism and D2R partial agonism may successfully target affective disorders in patients from different age groups without a risk of cognitive deficits. Expand
Arginine deprivation affects glioblastoma cell adhesion, invasiveness and actin cytoskeleton organization by impairment of β-actin arginylation
TLDR
The data indicate that arginine deprivation-based treatment strategies could inhibit, at least transiently, the invasion process of highly malignant brain tumors and may have a potential for combination therapy to extend overall patient survival. Expand
Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests
TLDR
It is suggested that EMD 386088, a 5- HT6 receptor agonist, produces anxiolytic-like activity after systemic administration which may result from direct stimulation of 5-HT6 receptors. Expand
Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats
TLDR
The obtained findings suggest that EMD 386088 produces antidepressant-like activity after systemic acute and chronic administration which may result from direct stimulation of 5-HT6 receptors. Expand
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