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The use of biomarkers in biomonitoring: a 2-tier approach assessing the level of pollutant-induced stress syndrome in sentinel organisms.
A simple spectrophotometric method for metallothionein evaluation in marine organisms: an application to Mediterranean and Antarctic molluscs
The use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approach.
Mechanisms of heavy metal cation homeostasis in marine invertebrates
Heavy metal effects on lipid peroxidation in the tissues of mytilus gallopro vincialis lam.
Heavy metals and glutathione metabolism in mussel tissues
Antioxidant role of metallothioneins: a comparative overview.
As the relevance of redox processes in cell signaling is becoming more and more evident, a search for MT effects on redox signaling could represent a turning point in the understanding of the functional role of these protein.
Genotoxicity biomarkers in the assessment of heavy metal effects in mussels: Experimental studies
- C. Bolognesi, E. Landini, P. Roggieri, R. Fabbri, A. Viarengo
- BiologyEnvironmental and molecular mutagenesis
The aim of this study was to evaluate the sensitivity of genotoxicity tests, alkaline elution and micronucleus test, as biomarkers for the detection of heavy metals in mussels as the sentinel species and a relationship between genotoxic effects and metallothionein content was observed.
Role of metallothionein against oxidative stress in the mussel Mytilus galloprovincialis.
- A. Viarengo, B. Burlando, M. Cavaletto, B. Marchi, E. Ponzano, J. Blasco
- BiologyAmerican journal of physiology. Regulatory…
- 1 December 1999
Data suggest an antioxidant role for MT, which seems to occur through oxyradical scavenging and is able to protect both isolated cells and the entire organism from oxidative stress.