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Efficacy predictors of lung volume reduction with Zephyr valves in a European cohort
The Endobronchial Valve for Emphysema Palliation Trial (VENT) was a multi-centre, prospective, randomised, controlled trial conducted to evaluate the safety and effectiveness of unilateralExpand
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Determinants of systemic vascular function in patients with stable chronic obstructive pulmonary disease.
RATIONALE Impaired vascular reactivity is an important factor in the pathogenesis of cardiovascular disease. OBJECTIVES We sought to assess vascular reactivity in patients with chronic obstructiveExpand
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Non-CPAP therapies in obstructive sleep apnoea
In view of the high prevalence and the relevant impairment of patients with obstructive sleep apnoea syndrome (OSAS) lots of methods are offered which promise definitive cures for or relevantExpand
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Circulating vascular endothelial growth factor and systemic inflammatory markers in patients with stable and exacerbated chronic obstructive pulmonary disease.
The aim of the present study was to assess circulating levels of VEGF (vascular endothelial growth factor), a biomarker with prognostic significance in cardiovascular disease, and markers of systemicExpand
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Bronchoscopic thermal vapour ablation therapy in the management of heterogeneous emphysema
The need for a less invasive procedure than surgical lung volume reduction that can produce consistent improvements with reduced morbidity remains a medical goal in patients with emphysema. We soughtExpand
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Symptomatic gastroesophageal reflux in subjects with a breathing sleep disorder.
STUDY OBJECTIVES A link between gastroesophageal reflux (GER) and obstructive sleep apnea (OSA) has been suggested; however, the prevalence and frequency of symptomatic GER and the influence of OSAExpand
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Effect of fissure integrity on lung volume reduction using a polymer sealant* in advanced emphysema
Rationale Interlobar fissure integrity has previously correlated with responsiveness to endobronchial lung volume reduction therapy in patients with advanced emphysema. Objective This reportExpand
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Heart rate variability and spontaneous baroreflex sequences in supine healthy volunteers subjected to nasal positive airway pressure.
To determine the dynamic effects of short-term nasal positive airway pressure (nPAP) on cardiovascular autonomic control, continuous recordings of noninvasively obtained hemodynamic measurements andExpand
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Phenotypes of COPD patients with a smoking history in Central and Eastern Europe: the POPE Study
Chronic obstructive pulmonary disease (COPD) represents a major health problem in Central and Eastern European (CEE) countries; however, there are no data regarding clinical phenotypes of theseExpand
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GOLD 2017 on the way to a phenotypic approach? Analysis from the Phenotypes of COPD in Central and Eastern Europe (POPE) Cohort
Recently, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) released a revised consensus report (2017 GOLD Report) [1] in which the formerly defined ABCD classification of patientsExpand
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