A. Val-Blasco

Publications27
h-index5
Citations68
Highly Influential Citations0
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • M. Fernández-Velasco
  • 78 Publications, 1,487 Citations
  • G. Núñez
  • 490 Publications, 77,043 Citations
  • G. Ruiz-Hurtado
  • 118 Publications, 1,128 Citations
  • P. Prieto
  • 46 Publications, 342 Citations
  • Publications
  • Influence
Role of NOD1 in Heart Failure Progression via Regulation of Ca2+ Handling.
BACKGROUND Heart failure (HF) is a complex syndrome associated with a maladaptive innate immune system response that leads to deleterious cardiac remodeling. However, the underlying mechanisms of… Expand
  • 20
Fibroblast growth factor-23 promotes rhythm alterations and contractile dysfunction in adult ventricular cardiomyocytes.
Background Cardiac dysfunction and arrhythmia are common and onerous cardiovascular events in end-stage renal disease (ESRD) patients, especially those on dialysis. Fibroblast growth factor (FGF)-23… Expand
  • 6
Intracellular calcium mishandling leads to cardiac dysfunction and ventricular arrhythmias in a mouse model of propionic acidemia.
Propionic acidemia (PA) is a rare metabolic disease associated with mutations in genes encoding the α and β subunits of the enzyme propionyl-CoA carboxylase. The accumulation of toxic metabolites… Expand
  • 4
NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes.
Cardiac fibrosis and chronic inflammation are common complications in type 2 diabetes mellitus (T2D). Since nucleotide oligomerization-binding domain 1 (NOD1), an innate immune receptor, is involved… Expand
  • 9
Beneficial effects of leptin treatment in a setting of cardiac dysfunction induced by transverse aortic constriction in mouse
Leptin, is a 16 kDa pleiotropic peptide not only primarily secreted by adipocytes, but also produced by other tissues, including the heart. Controversy exists regarding the adverse and beneficial… Expand
  • 9
Calcitriol (1,25-dihydroxyvitamin D3) increases L-type calcium current via protein kinase A signaling and modulates calcium cycling and contractility in isolated mouse ventricular myocytes.
BACKGROUND Calcitriol, the bioactive metabolite of vitamin D, exerts its effects through interaction with the nuclear vitamin D receptor (VDR) to induce genomic responses. Calcitriol may also induce… Expand
  • 7
Calcitriol (1, 25-Dihydroxy Vitamin D3) increases L-Type Calcium Current via PKA Signalling and Modulates Calcium Cycling and Contractility in Isolated Mouse Ventricular Myocytes
BACKGROUND: Calcitriol, the bioactive metabolite of vitamin D, exerts its effects through interaction with the nuclear vitamin D receptor (VDR) to induce genomic responses. Calcitriol may also induce… Expand
  • 1
  • PDF
Innate Immune Receptors, Key Actors in Cardiovascular Diseases
Central Illustration
  • 2
BML‐111 treatment prevents cardiac apoptosis and oxidative stress in a mouse model of autoimmune myocarditis
Myocarditis is an inflammation of the myocardium that can progress to a more severe phenotype of dilated cardiomyopathy (DCM). Three main harmful factors determine this progression: inflammation,… Expand
  • 2
Deficiency of NOD1 Improves the β-Adrenergic Modulation of Ca2+ Handling in a Mouse Model of Heart Failure
Heart failure (HF) is a complex syndrome characterized by cardiac dysfunction, Ca2+ mishandling, and chronic activation of the innate immune system. Reduced cardiac output in HF leads to compensatory… Expand
  • 4
  • PDF