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Central effects of the tetrapeptide tuftsin
The data obtained indicate direct relationships between tuftsin central effects and the changes in brain catecholaminergic processes participating in the regulation of emotional-motivational and motor reactions. Expand
Effect of subchronic administration of phenazepam and synthetic antioxidants on cerebral cortical synaptic membrane function of rats exposed to long-term stress
In the experiments on different animal species (mice, cats, dogs) lithium hydroxybutyrate has been shown to have antihypoxic and anti-ischemic effects. Lithium hydroxybutyrate improved the functionalExpand
[Post-stress correlation of the functional activity of macrophages by tuftsin and its derivatives].
Heptapeptide analog favoured the restoration of the macrophage activity after neurotization and stimulated lymphopoiesis and tuftsin did not restore the stress induced depression of macrophages activity but led to additional rise of the adrenal glands weight and to pronounced granulocyte-monocytosis. Expand
[Detection of the pro-opiomelanocortin peptide fragments--beta-endorphin and ACTH--in the adrenals of rats and mice by immunohistochemistry].
The data obtained suggest the existence of pituitary-independent mechanisms regulating corticosteroidogenesis in the adrenal gland, involving adrenal pro-opiomelanocortin fragments. Expand
[The effect of the deprivation of paradoxical sleep on the rotational and stereotyped behavior induced by selective agonists of the dopamine receptors].
It was found that REMSD SKF-38393 given along induced the ipsilateral rotation, and prolonged REMSD may induce nonidentical changes in the sensitivity of the postsynaptic D1 and D2 receptors. Expand
[Characteristics of the psychotropic spectrum of action of mebicar].
Under group interaction in cats, a new Soviet tranquilizer mebicar eliminates fear-alarm induced by stimulatin of the emotiogenic zone of the hypothalamus, and does not elicit cholinolytic action. Expand
[Effect of the N-terminal fragment of substance P1-4 on the somatic manifestations of the stress reaction and on the catecholamine content of the adrenals in rats].
It was ascertained that the preparation of protective effect is revealed to the greatest extent on the exhaustion stage (48 h of immobilization), which served to prevent the lymphoid organs mass reduction and ulcer development and also accounted for greater adrenaline and noradrenaline content preservation in tissues and chromaffin cells of adrenal glands in stressed animals. Expand