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Human Coronavirus NL63, France
Coronavirus NL63 was found in hospitalized children with upper and lower respiratory infections and it is believed that this virus may be responsible for some of the infections seen in these patients. Expand
Detection of the New Human Coronavirus HKU1: A Report of 6 Cases
The results suggest that HCoV-HKU1 could be associated with respiratory and enteric diseases, and its detection can be related to a persistent asymptomatic infection in patients with poor underlying conditions. Expand
Presence of the new human metapneumovirus in French children with bronchiolitis
We developed a polymerase chain reaction (PCR) to detect human metapneumovirus (hMPV) in French children hospitalized for acute respiratory tract disease during the winter of 2001 to 2002. This assayExpand
In Very Young Infants Severity of Acute Bronchiolitis Depends On Carried Viruses
The multivariate analyses showed that the type of virus carried was independently associated with the duration of hospitalization and underlined the role of RV in early respiratory diseases, as frequently carried by young infants with a first acute bronchiolitis. Expand
Comparison of multiplex PCR assays and conventional techniques for the diagnostic of respiratory virus infections in children admitted to hospital with an acute respiratory illness
The combined use of DFA and m‐PCR is today likely to be the best way to improve diagnosis of respiratory illnesses in children, according to the requirements of speed and low cost of the methods. Expand
Detection of viral, Chlamydia pneumoniae and Mycoplasma pneumoniae infections in exacerbations of asthma in children
These results confirm the previously reported high frequency of rhinovirus detection in asthmatic exacerbations in children, and point out the frequency of RS virus detection, and emphasize the fact that PCR assays may be necessary to diagnose respiratory infections in asthma. Expand
Comparative Evaluation of Six Commercialized Multiplex PCR Kits for the Diagnosis of Respiratory Infections
This study compared the practicability and the diagnostic performances of six CE-marked kits available in 2011 on the French market, including 2 detecting viruses and atypical bacteria and 4 detecting only viruses (from Abbott, Genomica, Qiagen and Seegene companies). Expand
Development of three multiplex RT-PCR assays for the detection of 12 respiratory RNA viruses
The overall sensitivity, rapidity and enhanced efficiency of these multiplex hemi-nested RT-PCR assays suggest that they would be a significant improvement over conventional methods for the detection of a broad spectrum of respiratory viruses. Expand
Congenital HCMV infection: a collaborative and comparative study of virus detection in amniotic fluid by culture and by PCR.
Antenatal virus diagnosis on amniotic fluid was negative with both techniques in 8 out of 29 cases of children born with HCMV infection, and over half of these wrongly negative results can be explained by amniocentesis carried out too early in the pregnancy or too early with respect to the mother's primary infection. Expand
Predictors of virologic failure and resistance in HIV-infected patients treated with nevirapine- or efavirenz-based antiretroviral therapy.
Patients' previous adherence to therapy and drugs genetic barriers, not only the number of pills or doses involved, should be taken into consideration in the decision to simplify highly active antiretroviral therapy. Expand