• Publications
  • Influence
The enniatin ionophores. Conformation and ion binding properties.
The ability of enniatins to bind alkali metal, alkaline earth metal and certain transition metal ions in solution has been investigated. The complexes have been shown to form in 1:1, 2:1 and 3:2Expand
  • 74
  • 4
Cyclodepsipeptides as chemical tools for studying ionic transport through membranes
SummaryThis paper reports a study of the chemistry of valinomycin, enniatins and related membrane-active depsipeptides that increase alkali metal ion permeability of model and biological membranes.Expand
  • 78
  • 2
Sandwich complexes as a functional form of the enniatin ionophores
The ability of the enniatin cyclodepsipeptides (CDP) (fig. 1) to form complexes with alkali metal ions (M+) and induce ionic permeability in artificial and biological membranes has been described inExpand
  • 67
  • 1
Topochemical Approach in Studies of the Structure–Activity Relation: Enantio-enniatin B
THE interaction of a biologically active substance with a selective receptor (for instance, substrate and enzyme) to cause a certain physiological effect is chemically complex, requiring not only aExpand
  • 30
Crystalline conformation of enniatin B
The spatial structure of the depsipeptide ionophoreenniatin B (fig.l) has been studied theoretically by semiempirical [1] and quantum-chemical PCILOmethods [2] as well as by solution techniques [3 -8Expand
  • 9
Theoretical conformational analysis of cyclic hexadepsipeptides. Enniatins
ConclusionsThe spatial conformation of the “polar” form of enniatin B has been established. A conformation of the N1 type has been proposed for the “nonpolar” form.
Conformation of enniatine B in nonpolar solvents
Conclusions1. The relative positions of the CαH and N-Ch3 signals in the1H NMR spectra of different conformers of enniatine B have been evaluated.2. The1H NMR spectra [tri-(N-methyl-D-valyl-Cα-d)]Expand