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Loss of E-cadherin Expression in Melanoma Cells Involves Up-regulation of the Transcriptional Repressor Snail*
Malignant transformation of melanocytes frequently coincides with loss of E-cadherin expression. Here we show that loss of E-cadherin in melanoma cell lines does not involve mutations in theExpand
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Discovery of LPMO activity on hemicelluloses shows the importance of oxidative processes in plant cell wall degradation
Significance Plant cell walls are recalcitrant copolymeric structures mainly comprising polysaccharides and lignin. Enzymatic degradation of the polysaccharides is a crucial step in biorefining ofExpand
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Carbohydrate-binding modules (CBMs) revisited: reduced amount of water counterbalances the need for CBMs
BackgroundA vast number of organisms are known to produce structurally diversified cellulases capable of degrading cellulose, the most abundant biopolymer on earth. The generally accepted paradigm isExpand
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Synergistic action of xylanase and mannanase improves the total hydrolysis of softwood.
The impact of xylan and glucomannan hydrolysis on cellulose hydrolysis was studied on five pretreated softwood substrates with different xylan and glucomannan contents, both varying from 0.2% toExpand
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Structural and Functional Characterization of a Lytic Polysaccharide Monooxygenase with Broad Substrate Specificity*
Background: The recently discovered lytic polysaccharide monooxygenases (LPMOs) are important in enzymatic conversion of lignocellulosic biomass. Results: We describe structural and functionalExpand
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Carbohydrate-binding modules of fungal cellulases: occurrence in nature, function, and relevance in industrial biomass conversion.
In this review, the present knowledge on the occurrence of cellulases, with a special emphasis on the presence of carbohydrate-binding modules (CBMs) in various fungal strains, has been summarized.Expand
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Oxidoreductases and Reactive Oxygen Species in Conversion of Lignocellulosic Biomass
Biomass constitutes an appealing alternative to fossil resources for the production of materials and energy. The abundance and attractiveness of vegetal biomass come along with challenges pertainingExpand
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Simultaneous analysis of C1 and C4 oxidized oligosaccharides, the products of lytic polysaccharide monooxygenases acting on cellulose.
Lytic polysaccharide monooxygenases play a pivotal role in enzymatic deconstruction of plant cell wall material due to their ability to catalyze oxidative cleavage of glycosidic bonds. LPMOs mayExpand
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Adsorption of monocomponent enzymes in enzyme mixture analyzed quantitatively during hydrolysis of lignocellulose substrates.
The adsorption of purified Trichoderma reesei cellulases (TrCel7A, TrCel6A and TrCel5A) and xylanase TrXyn11 and Aspergillus niger β-glucosidase AnCel3A was studied in enzyme mixture duringExpand
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Cellulases without carbohydrate-binding modules in high consistency ethanol production process
BackgroundEnzymes still comprise a major part of ethanol production costs from lignocellulose raw materials. Irreversible binding of enzymes to the residual substrate prevents their reuse and noExpand
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