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The sitting position in neurosurgery: indications, complications and results. a single institution experience of 600 cases
BackgroundThe benefit of the sitting position for surgery of the posterior fossa and cervical spine is still a matter of controversy. In our study we analyzed the outcome after sitting positionExpand
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Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents.
Induction of peripheral inflammation increases the expression of the Nav1.7 sodium channel in sensory neurons, potentially increasing their excitability. Peripheral inflammation also producesExpand
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Shaped magnetic field pulses by multi-coil repetitive transcranial magnetic stimulation (rTMS) differentially modulate anterior cingulate cortex responses and pain in volunteers and fibromyalgia
BackgroundRepetitive transcranial magnetic stimulation (rTMS) has shown promise in the alleviation of acute and chronic pain by altering the activity of cortical areas involved in pain sensation.Expand
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Propofol in rats: testing for nonlinear pharmacokinetics and modelling acute tolerance to EEG effects.
BACKGROUND AND OBJECTIVE Pharmacokinetics of propofol in rats have usually been described using linear models. Furthermore, there are only a few investigations for a pharmacodynamic model of theExpand
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Selective nociceptor activation in volunteers by infrared diode laser
BackgroundTwo main classes of peripheral sensory neurons contribute to thermal pain sensitivity: the unmyelinated C fibers and thinly myelinated Aδ fibers. These two fiber types may differentiallyExpand
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Differential activation of trigeminal C or Aδ nociceptors by infrared diode laser in rats: behavioral evidence
Radiant heat is often used for studying thermal nociception, although inherent characteristics such as the broad spectrum of applied wavelengths of typical light sources limit control over andExpand
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National and International Guidelines for Patient Blood Management in Obstetrics: A Qualitative Review
In developed countries, rates of postpartum hemorrhage (PPH) requiring transfusion have been increasing. As a result, anesthesiologists are being increasingly called upon to assist with theExpand
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Oxytocin and Migraine Headache
This article reviews material presented at the 2016 Scottsdale Headache Symposium. This presentation provided scientific results and rationale for the use of intranasal oxytocin for the treatment ofExpand
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Visualizing Dermal Permeation of Sodium Channel Modulators by Mass Spectrometric Imaging
Determining permeability of a given compound through human skin is a principal challenge owing to the highly complex nature of dermal tissue. We describe the application of an ambient massExpand
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EEG-controlled closed-loop dosing of propofol in rats.
BACKGROUND Based on previous pharmacokinetic and pharmacodynamic studies, we have developed an EEG-controlled closed-loop system for the i.v. hypnotic agent propofol in rats. METHODS Seven adultExpand
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