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Modern techniques have reduced the frequency of infections that are associated with prosthetic joints, but such infections continue to pose difficult problems in clinical management. Advances in… Expand
Sonication of removed hip and knee prostheses for diagnosis of infection.
BACKGROUND Culturing of samples of periprosthetic tissue is the standard method used for the microbiologic diagnosis of prosthetic-joint infection, but this method is neither sensitive nor specific.… Expand
Clinical review: Severe malaria
Malaria represents a medical emergency because it may rapidly progress to complications and death without prompt and appropriate treatment. Severe malaria is almost exclusively caused by Plasmodium… Expand
Synovial fluid leukocyte count and differential for the diagnosis of prosthetic knee infection.
- A. Trampuz, A. Hanssen, D. Osmon, J. Mandrekar, J. Steckelberg, R. Patel
- The American journal of medicine
- 15 October 2004
PURPOSE Criteria for the interpretation of synovial fluid are well established for native joint disorders but lacking for the evaluation of prosthetic joint failure. Our aim was to define cutoff… Expand
Prosthetic joint infections: update in diagnosis and treatment.
The pathogenesis of prosthetic joint infection is related to microorganisms growing in biofilms, rendering these infections difficult to diagnose and to eradicate. Low-grade infections in particular… Expand
Improved Diagnosis of Periprosthetic Joint Infection by Multiplex PCR of Sonication Fluid from Removed Implants
- Y. Achermann, M. Vogt, M. Leunig, J. Wüst, A. Trampuz
- Biology, Medicine
- Journal of Clinical Microbiology
- 17 February 2010
ABSTRACT The microbiological diagnosis of periprosthetic joint infection (PJI) is crucial for successful antimicrobial treatment. Cultures have limited sensitivity, especially in patients receiving… Expand
Prevalence and risk factors for nosocomial infections in four university hospitals in Switzerland.
OBJECTIVE To determine the prevalence and risk factors for nosocomial infections (NIs) in four Swiss university hospitals. DESIGN AND SETTING A 1-week period-prevalence survey conducted in May 1996… Expand
Infections associated with orthopedic implants
Purpose of review We review recent advances in the prevention, diagnosis and treatment of infections associated with joint prostheses and internal fixation devices. Recent findings The perioperative… Expand
Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults: a retrospective analysis over an 11-year period.
- A. Conen, Laura N Walti, A. Merlo., U. Flúckiger, M. Battegay, A. Trampuz
- Clinical infectious diseases : an official…
- 1 July 2008
BACKGROUND Data on infections associated with cerebrospinal fluid (CSF) shunts among adults are limited. Therefore, we performed a retrospective study of shunt-associated infections in adults. … Expand
Molecular and antibiofilm approaches to prosthetic joint infection.
- A. Trampuz, D. Osmon, A. Hanssen, J. Steckelberg, R. Patel
- Clinical orthopaedics and related research
- 1 September 2003
The majority of patients with prosthetic joint replacement (arthroplasty) experience dramatic relief of pain and restoration of satisfactory joint function. In the United States, more than.5 million… Expand