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Systematic review and meta‐analysis of outcomes following emergency surgery for Clostridium difficile colitis
The aim of this study was to describe the operations performed and to identify factors predictive of death following emergency surgery for CDI. Expand
Has integrated 18F FDG PET/CT improved staging, reduced early recurrence or increased survival in oesophageal cancer?
PET/CT has improved the accuracy of oesophageal cancer staging avoiding potentially unnecessary surgery, however, its use has had no effect on early recurrence or survival rates. Expand
Meta-analysis of temporary loop ileostomy closure during or after adjuvant chemotherapy following rectal cancer resection: the dilemma remains
The meta-analysis of the best, albeit limited, available evidence suggests that temporary loop ileostomy closure during adjuvant chemotherapy following rectal cancer resection may be associated with comparable outcomes to the closure of ilestomy after adjuant chemotherapy. Expand
Emergency surgery in the elderly: challenges and solutions
20 years of reports by various medical bodies that have aimed to improve the care of elderly patients with surgical emergencies are summarized and specific challenges in caring for these patients are highlighted. Expand
Meta-analysis of transanal total mesorectal excision versus laparoscopic total mesorectal excision in management of rectal cancer
Although the meta-analysis of best available evidence demonstrated that TaTME may be associated with better short-term oncological outcomes and similar clinical outcomes compared with LaTME, the differences between the two groups were small questioning their clinical relevance. Expand
Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial
  • Aneel Dmitri Natalie Laura James Colm Thue Kelly Samir D Bhangu Nepogodiev Ives Magill Glasbey Forde Bisgaa, A. Bhangu, +395 authors Ly-Mee Yu
  • Medicine
  • The Lancet
  • 8 February 2020
The results of this study support the use of biological mesh in stoma closure site reinforcement to reduce the early formation of incisional hernias and with an acceptable safety profile. Expand
Feasibility work to inform the design of a randomized clinical trial of wound dressings in elective and unplanned abdominal surgery
This study aimed to assess how feasibility work could inform the design of a future pilot study and RCT in surgery. Expand
Oncological outcomes of abdominoperineal resection for the treatment of low rectal cancer: A retrospective review of a single UK tertiary centre experience
Positive circumferential resection margin following APR resulted in significantly increased local recurrence with a trend towards poorer survival outcomes, which would recommend selective use of Extralevator abdominoperineal resection for locally advanced and node-positive tumours. Expand
Meta-analysis of medial-to-lateral versus lateral-to-medial colorectal mobilisation during laparoscopic colorectal surgery
The meta-analysis showed that medial-to-lateral approach during laparoscopic colorectal resection may reduce procedure time, length of hospital stay and conversion to open procedure rate, and it may probably reduce overall perioperative morbidity. Expand
C-reactive protein can predict anastomotic leak in colorectal surgery: a systematic review and meta-analysis
The cut-off CRP values can be used to predict AL to expedite investigation and treatment and study heterogeneity, some characteristics unreported, no RCT AL is associated with higher CRP levels on each post-operative day compared to no AL after colorectal surgery. Expand