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Structural basis of heteromeric smad protein assembly in TGF-beta signaling.
The formation of protein complexes between phosphorylated R-Smads and Smad4 is a central event in the TGF-beta signaling pathway. We have determined the crystal structure of two R-Smad/Smad4Expand
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Structural Basis of Heteromeric Smad Protein Assembly in TGF-β Signaling
The formation of protein complexes between phosphorylated R-Smads and Smad4 is a central event in the TGF-β signaling pathway. We have determined the crystal structure of two R-Smad/Smad4 complexes,Expand
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Microwave-accelerated synthesis and characterization of potato starch-g-poly(acrylamide)
Using a very low concentration of potassium persulfate as initiator, acrylamide could be efficiently grafted onto potato starch under microwave irradiation and for the grafting O 2 removal from theExpand
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First structural evidence for the mode of diffusion of aromatic ligands and ligand-induced closure of the hydrophobic channel in heme peroxidases
The mode of binding of aromatic ligands in the substrate binding site on the distal heme side in heme peroxidases is well understood. However, the mode of diffusion through the extended hydrophobicExpand
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Stabilization of yeast hexokinase A by polyol osmolytes: correlation with the physicochemical properties of aqueous solutions.
Osmolytes of the polyol series are known to accumulate in biological systems under stress and stabilize the structures of a wide variety of proteins. While increased surface tension of aqueousExpand
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Microwave synthesized chitosan-graft-poly(methylmethacrylate): An efficient Zn2+ ion binder
Abstract Microwave promoted grafting of methylmethacrylate on to the chitosan has been optimized. Chitosan- graft -poly(methylmethacrylate) (Ch- g -PMMA) could be synthesized with 160% grafting usingExpand
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Poly(acrylonitrile) grafted Ipomoea seed-gums: a renewable reservoir to industrial gums.
Plants of Ipomoea genus are widely distributed in India as wild vegetation and are reported source for the seed gums. Seed gums from Ipomoea dasysperma, Ipomoea hederacea, and Ipomoea palmata plantsExpand
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An Amphiphilic Nanocarrier Based on Guar Gum-graft-Poly(ε-caprolactone) for Potential Drug-Delivery Applications
Amphiphilic guar gum grafted with poly(ε-caprolactone) (GG-g-PCL) was fabricated as a drug-delivery carrier using microwave irradiation. The structure of the GG-g-PCL co-polymer was characterized byExpand
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Synthesis of Chemical Responsive Chitosan–Grafted-Polyaniline Bio-Composite
A polysaccharide based bioplolymer, chitosan was grafted with polyaniline through a simple room temperature oxidative-radical copolymerization method employing CuSO4 as a polymerizing agent. TheExpand
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Microwave accelerated synthesis and characterization of poly(acrylamide)
Poly(acrylamide) (PAM) was efficiently synthesized under microwave (MW) irradiation using catalytic amount of potassium persulfate. The synthesis does not require any inert atmosphere and could beExpand
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