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Apical Membrane Antigen 1, a Major Malaria Vaccine Candidate, Mediates the Close Attachment of Invasive Merozoites to Host Red Blood Cells
TLDR
Apical membrane antigen 1 of Plasmodium merozoites may be directly responsible for reorientation or that the molecule may initiate the junctional contact, which is then presumably dependent on Duffy binding proteins for its completion.
Origin of Plasmodium falciparum malaria is traced by mitochondrial DNA.
The genome of the simian and human malaria parasite Plasmodium knowlesi
TLDR
This is the first monkey malaria parasite genome to be described, and it provides an opportunity for comparison with the recently completed P. vivax genome and other sequenced Plasmodium genomes.
Antibodies to glycans dominate the host response to schistosome larvae and eggs: is their role protective or subversive?
TLDR
The antiglycan responses resulting from infection could be a smoke screen to subvert the immune system away from more vulnerable larval peptide epitopes, and explain the long time required for antischistosome immunity to build up after infection.
High prevalence of natural antibodies against Plasmodium falciparum 83-kilodalton apical membrane antigen (PF83/AMA-1) as detected by capture-enzyme-linked immunosorbent assay using full-length
TLDR
Analysis of populations from villages in Guinea-Bissau and in an area of high malarial transmission in Senegal demonstrated a very high prevalence of naturally acquired serum IgG responses to PF83/AMA-1, showing that PF83-7G8-1 may be a well-recognized asexual parasite antigen.
Plasmodium knowlesi: secondary processing of the malaria merozoite surface protein-1.
TLDR
It is reported that secondary processing of MSP-1 takes place in a similar manner on invasive merozoites of the simian malaria parasite Plasmodium knowlesi and the nucleotide sequence of the 3' domain of the P. knowlesi MSP1 gene is presented.
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