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Clinical Pharmacokinetics of Lercanidipine
Lercanidipine has one of the highest measured membrane partition coefficients for any calcium antagonist to date and supports the long‐lasting pharmacologic activity observed.
Lercanidipine (Rec 15/2375): A Novel 1,4‐Dihydropyridine Calcium Antagonist for Hypertension
Although significant progress has been made in the prevention and treatment of hypertension, the problem is still far from being completely clarified and solved.
Hemorrhoidectomy according to Milligan-Morgan: ligature and excision technique.
  • A. Tajana
  • Medicine
    International surgery
  • 1 July 1989
Correct indication and a precise, accurate technique based upon the high ligature of the vascular peduncle and on the preservation of the muco-skin bridges are the essential conditions for the radicality of the intervention in 97% of the cases and for a minimum incidence of morbility.
Synthesis and anticonvulsant activity of N-(benzoylalkyl)imidazoles and N-(omega-phenyl-omega-hydroxyalkyl)imidazoles.
A novel series of N-(benzoylalkyl)imidazoles and N-(omega-phenyl-omego-hydroxyalkyl)-substitute for phenytoin and phenobarbital was synthesized and evaluated for anticonvulsant activity in mice against maximal electroshock induced seizures.
Determination of nifurpipone in urine.
Nifurpipone (5-nitrofuraldehyde-N′-methylpiperazino-acetylhydrazone) in urine was selectively adsorbed and eluted from cationic resin with methanolic ammonium hydroxide solution. The drug in the
New basic esters of 2-phenyl-3-methyl-4-oxo-4H-1-benzopyran-8-carboxylic acid endowed with spasmolytic properties. Synthesis and pharmacological-pharmacokinetic evaluation.
The deeper pharmacological characterization of this compound, carried out mainly in comparison with flavoxate, terodiline, and oxybutynin confirmed its good spasmolytic activity.