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Herpes Simplex Virus ICP27 Protein Directly Interacts with the Nuclear Pore Complex through Nup62, Inhibiting Host Nucleocytoplasmic Transport Pathways*
Background: Several aspects of herpes simplex virus ICP27 trafficking remain unclear. Results: We investigated if ICP27 could interact with the nuclear pore complex, finding that ICP27 directly bindsExpand
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Mutations in the S gene region of hepatitis B virus genotype D in Golestan Province-Iran
Mutations of HBsAg especially within the “a” determinant could alter the antigenicity of the protein causing failure of HBsAg neutralization and escaping from the host’s immune system, resulting inExpand
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Epigallocatechin‐3‐gallate enhances differentiation of acute promyelocytic leukemia cells via inhibition of PML‐RARα and HDAC1
The use of all‐trans retinoic acid (ATRA) has dramatically improved the treatment and survival rate of patients with acute promyelocytic leukemia (APL). However, toxicity and resistance to this drugExpand
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Nanomolecular detection of human influenza virus type A using reverse transcription loop-mediated isothermal amplification assisted with rod-shaped gold nanoparticles
Reverse transcription loop-mediated isothermal amplification (RT-LAMP) and rod-shaped gold nanoparticles (gold nanorods; GNRs) were employed for nanomolecular detection of human influenza virus typeExpand
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Concurrent infections of hepatitis C and HIV in hepatitis B patients in the north-east of Iran
Co-infection of HBV, HCV and HIV is common because of shared routes of viral transmission with increased risk of morbidity and mortality. Anti-HCV and HIV antibodies of 168 HBV patients were assayed.Expand
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Clinical and Epidemiological Profile of Pandemic Influenza A H1N1, H3N2, and Type B in the Southeast of Caspian Sea, Iran
Background: Timely diagnosis of influenza virus is important because this virus can cause severe illness. The 2009 pdmH1N1 influenza virus spread rapidly throughout the world as the first infectiousExpand
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Enhanced cell immune responses to hepatitis c virus core by novel heterologous DNA prime/lambda nanoparticles boost in mice
Hepatitis C virus (HCV) is a worldwide problem which does not have an effective vaccine and more than 170 million people worldwide are chronically infected by HCV. T cell responses are associatedExpand
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Newborn Screening for Congenital Cytomegalovirus Infection in Iran.
To the Editor:The prevalence of cytomegalovirus (CMV) infection at birth is between 0.6% and 0.7% in developed countries and between 1% and 5% in developing countries and 10% to 15% infected infantsExpand
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Human cytomegalovirus pUL97 drug-resistance mutations in congenitally neonates and HIV-infected, no-drug-treated patients
Aim: Human cytomegalovirus (HCMV) treatment is hard to achieve because of viral protein target sequence variations. Objectives: We aimed to find HCMV pUL97 kinase variations in HIV- and congenitallyExpand
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Hepatitis B virus reverse transcriptase polymorphisms between treated and treatment-naïve chronically infected patients
AbstractThe aim of this study was investigation of variation(s) in the Hepatitis B virus (HBV) reverse transcriptase domain. 120 patients with chronic HBV infection recruited. 104 patients wereExpand
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