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Distal symmetric polyneuropathy: A definition for clinical research
TLDR
A formalized consensus process was employed to reach agreement after a systematic review and classification of evidence from the literature that indicated symptoms alone have relatively poor diagnostic accuracy in predicting the presence of polyneuropathy. Expand
Practice Parameter: Evaluation of distal symmetric polyneuropathy: Role of laboratory and genetic testing (an evidence-based review)
TLDR
Initial genetic testing should be guided by the clinical phenotype, inheritance pattern, and electrodiagnostic features and should focus on the most common abnormalities which are CMT1A duplication/HNPP deletion, Cx32 (GJB1), and MFN2 mutation screening. Expand
Multifocal demyelinating neuropathy with persistent conduction block
TLDR
Four patients with a chronic asymmetric sensorimotor neuropathy most pronounced in the upper extremities with focal involvement of individual nerves had acute optic neuritis, indicating that the disorder was not always restricted to the peripheral nervous system. Expand
Practice Parameter: Evaluation of distal symmetric polyneuropathy: Role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review)
TLDR
There is a need for additional prospective studies to define more exact guidelines regarding the role of autonomic testing, nerve biopsy, and skin biopsy for the assessment of polyneuropathy. Expand
Distal accentuation of conduction slowing in polyneuropathy associated with antibodies to myelin-associated glycoprotein and sulphated glucuronyl paragloboside.
TLDR
Recognition of this unique pattern of generalized, distally predominant conduction slowing in anti-MAG/SGPG polyneuropathy may be useful in clinically distinguishing this from other chronic demyelinatingpolyneuropathies, and in possibly providing insights into the pathophysiology of this disorder. Expand
Wasting of the hand associated with a cervical rib or band 1
TLDR
Nine patients are described with unilateral wasting of the hand muscles associated with elongated C7 transverse processes or with rudimentary cervical ribs, in which a sharp fibrous band was found at operation and division of the fibrousBand relieved pain and paraesthesiae in eight patients and arrested muscle wasting and weakness in nine patients. Expand
A syndrome of asymmetric limb weakness with motor conduction block
TLDR
3 patients with asymmetric limb weakness, fasciculations, relatively preserved reflexes, normal cranial nerves, and few or no sensory abnormalities are described, indicating very selective involvement of motor fibers. Expand
Experimental allergic neuritis induced by sensitization with galactocerebroside.
Thirteen of 31 rabbits immunized repeatedly with bovine brain galactocerebroside developed experimental allergic neuritis, manifested by flaccid paresis and hypesthesia of four limbs, 2 to 11 monthsExpand
A computer simulation of conduction block: Effects produced by actual block versus interphase cancellation
TLDR
Measurements of CMAP amplitude and area may be misleading if there is significant abnormal temporal dispersion, and quantitation of the degree of conduction block is difficult without knowledge of which subpopulations of axons are affected. Expand
Evaluation of distal symmetric polyneuropathy: The role of autonomic testing, nerve biopsy, and skin biopsy (an evidence‐based review)
TLDR
There is a need for additional prospective studies to define more exact guidelines regarding the role of autonomic testing, nerve biopsy, and skin biopsy for the assessment of polyneuropathy. Expand
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