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A dynein loading zone for retrograde endosome motility at microtubule plus‐ends
In the fungus Ustilago maydis, early endosomes move bidirectionally along microtubules (MTs) and facilitate growth by local membrane recycling at the tip of the infectious hypha. Here, we set out toExpand
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A balance of KIF1A‐like kinesin and dynein organizes early endosomes in the fungus Ustilago maydis
In Ustilago maydis, bidirectional transport of early endosomes is microtubule dependent and supports growth and cell separation. During early budding, endosomes accumulate at putative microtubuleExpand
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Dynein supports motility of endoplasmic reticulum in the fungus Ustilago maydis.
The endoplasmic reticulum (ER) of most vertebrate cells is spread out by kinesin-dependent transport along microtubules, whereas studies in Saccharomyces cerevisiae indicated that motility of fungalExpand
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Coordination of adjacent domains mediates TACC3–ch-TOG–clathrin assembly and mitotic spindle binding
Aurora A phosphorylation-induced interaction of TACC3 and clathrin coordinates adjacent domains in each protein to create a microtubule-binding interface, whereas a distinct site in TACC3 recruitsExpand
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MAP4 and CLASP1 operate as a safety mechanism to maintain a stable spindle position in mitosis
Correct positioning of the mitotic spindle is critical to establish the correct cell-division plane. Spindle positioning involves capture of astral microtubules and generation of pushing/pullingExpand
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Microtubule organization requires cell cycle-dependent nucleation at dispersed cytoplasmic sites: polar and perinuclear microtubule organizing centers in the plant pathogen Ustilago maydis.
Growth of most eukaryotic cells requires directed transport along microtubules (MTs) that are nucleated at nuclear-associated microtubule organizing centers (MTOCs), such as the centrosome and theExpand
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EB3 Regulates Microtubule Dynamics at the Cell Cortex and Is Required for Myoblast Elongation and Fusion
Summary During muscle differentiation, myoblasts elongate and fuse into syncytial myotubes [1]. An early event during this process is the remodeling of the microtubule cytoskeleton, involvingExpand
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A novel mechanism of nuclear envelope break‐down in a fungus: nuclear migration strips off the envelope
In animals, the nuclear envelope disassembles in mitosis, while budding and fission yeast form an intranuclear spindle. Ultrastructural data indicate that basidiomycetes, such as the pathogenExpand
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Microtubules in cell migration
Abstract Directed cell migration is critical for embryogenesis and organ development, wound healing and the immune response. Microtubules are dynamic polymers that control directional migrationExpand
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Directional persistence of migrating cells requires Kif1C-mediated stabilization of trailing adhesions.
Directional cell migration requires the establishment and maintenance of long-term differences in structure and function between the front and back of a cell. Here, we show that the microtubule motorExpand
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