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Gene expression profiling of primary cutaneous melanoma and clinical outcome.
BACKGROUND Gene expression profiling data for human primary cutaneous melanomas are scarce because of the lack of retrospective collections of frozen tumors. To identify differentially expressedExpand
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Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects.
Mutant isoforms of the KIT or PDGF receptors expressed by gastrointestinal stromal tumors (GISTs) are considered the therapeutic targets for STI571 (imatinib mesylate; Gleevec), a specific inhibitorExpand
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Phase III trial comparing adjuvant treatment with pegylated interferon Alfa-2b versus observation: prognostic significance of autoantibodies--EORTC 18991.
PURPOSE Conflicting data have been reported concerning the prognostic value of autoimmune antibodies in patients with melanoma treated with adjuvant interferon alfa-2b (IFN). We evaluated theExpand
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Étude clinique et recherche de mutations germinales du gène PTCH 1 dans le syndrome des hamartomes basocellulaires
Resume Introduction La naevomatose basocellulaire ou syndrome des hamartomes basocellulaires est une genodermatose de transmission autosomique dominante caracterisee par des anomalies duExpand
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Mélanomes du pénis : 6 cas
Resume Introduction Les melanomes du penis sont des tumeurs rares et de mauvais pronostic. Methodes Six cas de melanome du penis repertories entre 1975 et 2002 ont ete etudies retrospectivement. NousExpand
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La lame virtuelle en pathologie
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Intérêt du ganglion sentinelle dans le carcinome de Merkel
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C92 - Association mélanome et cancer du rein