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Engineered human carboxypeptidase B enzymes that hydrolyse hippuryl-L-glutamic acid: reversed-polarity mutants.
TLDR
Variants of human pancreatic carboxypeptidase B prepared by site-directed mutagenesis of the human gene and expressed in the periplasm of Escherichia coli have the potential to be used in antibody-directed enzyme prodrug therapy of cancer. Expand
L-Sorbose phosphorylation in Escherichia coli K-12.
TLDR
L-Sorbose is phosphorylated by Escherichia coli by two distinct Enzymes II of the phosphoenolpyruvate-dependent phosphotransferase system, but sorbose inhibits the growth of strains expressing either of these functions constitutively. Expand
G-quadruplex ligands mediate downregulation of DUX4 expression
TLDR
It is demonstrated for the first time that GQs are present in the DUX4 locus and that the GQ interactive ligand reduces Dux4 expression suggesting potential role of G Qs in FSHD pathogenesis. Expand
MELANOPLEUROIDES DOMINICANUS, A NEW LYGAEINE GENUS AND SPECIES FROM THE DOMINICAN REPUBLIC (HETEROPTERA: LYGAEIDAE)
Melanopleuroides dominicanus is described from the Dominican Republic. Characteristics to separate it from similar taxa, genitalic drawings, and a brief discussion of its phylogenetic relationshipsExpand
Biophysical studies of the interaction between high molecular weight kininogen and gC1q-R : initiating the contact pathway
The contact pathway is part of the coagulation pathway involved in haemosta- sis. It is responsible for the deposition of fibrin fibres during blood coagulation as well as the production of theExpand
Taxonomic Notes on Lygaeinae from Australia and Neighboring Areas (Heteroptera: Lygaeidae)
TLDR
The genus Montaltus Distant is synonymized with Astacops Boisduval, and most species of the Caenocoris complex are placed generically. Expand
A NEW SPECIES OF MYODOCHA (HEMIPTERA: LYGAEIDAE: RHYPAROCHROMINAE: MYODOCHINI) FROM THE WEST INDIES
Myodocha froeschneri n. sp. is described based on specimens from Dominican Republic, Haiti, and Jamaica.