• Publications
  • Influence
Prognostic significance of elevated cyclooxygenase-2 expression in breast cancer.
Cyclooxygenase-2 (Cox-2) expression can induce mammary tumorigenesis in transgenic mice, and selective Cox-2 inhibitors are both chemopreventive and chemotherapeutic in rat models of breast cancer.Expand
Cyclooxygenase‐2 and gastric carcinogenesis
Epidemiological studies have shown that the use of nonsteroid anti‐inflammatory drugs (NSAIDs) is associated with reduced risk of gastric cancer. The best‐known target of NSAIDs is the cyclooxygenaseExpand
Association of cyclooxygenase-2 and matrix metalloproteinase-2 expression in human breast cancer
SummaryExpression of cyclooxygenase-2 (COX-2) and matrix metalloproteinase-2 (MMP-2) associates with reduced survival in human breast cancer. COX-2 may be directly involved with mammaryExpand
Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagus.
BACKGROUND & AIMS Use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced risk of cancer in the digestive tract. Cyclooxygenase (COX) is the best-known target of NSAIDs, andExpand
Cytoplasmic HuR expression correlates with epithelial cancer cell but not with stromal cell cyclooxygenase-2 expression in mucinous ovarian carcinoma.
UNLABELLED Cyclooxygenase-2 (COX-2) expression has been found to associate with poor prognosis in several types of carcinomas. HuR is an mRNA stability protein and it regulates the expression ofExpand
Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.
Cyclooxygenase-2 (COX-2) expression has been shown to associate with poor prognosis in ovarian cancer, and an mRNA stability protein HuR has been shown to enhance expression of COX-2 in tissueExpand
Expression of microsomal prostaglandin E synthase‐1 in intestinal type gastric adenocarcinoma and in gastric cancer cell lines
Gastrointestinal carcinomas synthesize elevated levels of prostaglandin E2 (PGE2), which has been mechanistically linked to carcinogenesis. Recently, microsomal prostaglandin E synthase‐1 (mPGES‐1)Expand
Prognostic role of cyclooxygenase‐2 in neoadjuvant‐treated patients with squamous cell carcinoma of the esophagus
Based on our previous demonstration that elevated cyclooxygenase‐2 (COX‐2) expression is a prognostic factor for reduced survival in patients with adenocarcinoma of the esophagus, the aim of ourExpand
COX-2 in cancer
Multiple epidemiological studies indicate that the use of aspirin and other NSAIDs are associated with reduced risk of malignancies especially in the digestive tract. In addition, another NSAIDExpand
Comparison of cyclooxygenase 2 expression in adenocarcinomas of the gastric cardia and distal oesophagus
Background: Adenocarcinomas of the gastric cardia and distal oesophagus are at present often considered as one clinical entity because of their comparable increasing incidence, prognosis, and optimalExpand
...
1
2
3
...