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Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
Oxidative stress has been postulated to play an important role in the pathogenesis of asthma; although a defect in antioxidant responses has been speculated to exacerbate asthma severity, this hasExpand
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Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth
Loss-of-function mutations in the nuclear factor erythroid-2–related factor 2 (Nrf2) inhibitor Kelch-like ECH-associated protein 1 (Keap1) result in increased Nrf2 activity in non–small cell lungExpand
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Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome-like skeletal defects induced by Pdk1 or Cbp mutations in mice.
Mutations in the coactivator CREB-binding protein (CBP) are a major cause of the human skeletal dysplasia Rubinstein-Taybi syndrome (RTS); however, the mechanism by which these mutations affectExpand
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A Survey of Association Rule Hiding Algorithms
The significant development in field of data collection and data storage technologies have provided transactional data to grow in data warehouses that reside in companies and public sectorExpand
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K-Partition Model for Mining Frequent Patterns in Large Databases
Mining frequent patterns has always been a great field of research for investigators. Various algorithms were developed for finding out frequent patterns in an efficient manner. But the majorExpand
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Dysregulated invertebrate tropomyosin–dectin-1 interaction confers susceptibility to allergic diseases
Invertebrate tropomyosin homologs are ligands for dectin-1. Dectin-1 limits allergic responses Aberrant activation of pattern recognition receptors (PRRs) drives inflammation in autoimmune andExpand
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Optimizing network traffic by generating association rules using hybrid apriori-genetic algorithm
Association rule mining is a technique of generating frequent item sets so that the analysis on the basis of these sets can be used for different application areas such as analysis of networkExpand
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Knowledge Based Retrieval Scheme from Big Data for Aviation Industry
Big-data middle layer architecture is defined to perform the query analysis and the evaluation of the Big Data. This scheme is implemented on dynamic generated data section. The concept of Big DataExpand
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A triple stranded G-quadruplex formation in the promoter region of human myosin β(Myh7) gene
  • A. Singh, S. Kukreti
  • Chemistry, Medicine
  • Journal of biomolecular structure & dynamics
  • 1 August 2018
Regulatory regions in human genome, enriched in guanine-rich DNA sequences have the propensity to fold into G-quadruplex structures. On exploring the genome for search of G-tracts, it was interestingExpand
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Result Analysis Using Classification Techniques
Mining is a powerful tool for academic intervention. The educational institutions can use classification for comprehensive analysis of students" characteristics. In our work, we collected student"sExpand
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