Genetics of Parkinson's Disease: Genotype-Phenotype Correlations.
- C. Koros, A. Simitsi, L. Stefanis
- BiologyInternational review of neurobiology
- 2017
Serotonergic pathology and disease burden in the premotor and motor phase of A53T α-synuclein parkinsonism: a cross-sectional study
- H. Wilson, G. Dervenoulas, M. Politis
- Medicine, BiologyLancet Neurology
- 1 August 2019
A Novel SNCA A30G Mutation Causes Familial Parkinsonʼs Disease
The SNCA gene encoding α‐synuclein (αSyn) is the first gene identified to cause autosomal‐dominant Parkinsonʼs disease (PD).
Selective cognitive impairment and hyposmia in p.A53T SNCA PD vs typical PD
- C. Koros, M. Stamelou, L. Stefanis
- Medicine, PsychologyNeurology
- 6 March 2018
The observed selective cognitive impairment reflecting frontal-parietal network dysfunction, together with impaired olfaction, define a set of nonmotor dysfunctions related to A53T PD that have implications for the prognosis of patients with A 53T PD.
Circulating Brain‐Enriched MicroRNAs for Detection and Discrimination of Idiopathic and Genetic Parkinson's Disease
- S. Ravanidis, A. Bougea, E. Doxakis
- BiologyMovement Disorders
- 4 December 2019
It is now known that the differential expression of neuron‐enriched miRNAs leads to brain dysfunction.
Alpha-synuclein dimerization in erythrocytes of patients with genetic and non-genetic forms of Parkinson’s Disease
- N. Papagiannakis, C. Koros, L. Stefanis
- Medicine, BiologyNeuroscience Letters
- 1 November 2017
Frontotemporal dementia as the presenting phenotype of p.A53T mutation carriers in the alpha-synuclein gene.
- A. Bougea, C. Koros, L. Stefanis
- Psychology, BiologyParkinsonism & Related Disorders
- 1 February 2017
Validation of differentially expressed brain‐enriched microRNAs in the plasma of PD patients
- S. Ravanidis, A. Bougea, E. Doxakis
- BiologyAnnals of Clinical and Translational Neurology
- 29 August 2020
The aim of the present study was to validate a set of previously identified brain‐enriched miRNAs with diagnostic potential for idiopathic PD and recognize the molecular pathways affected by these deregulated mi RNAs.
The relationship between environmental factors and different Parkinson's disease subtypes in Greece: Data analysis of the Hellenic Biobank of Parkinson's disease.
- Efthalia Angelopoulou, M. Bozi, L. Stefanis
- Biology, MedicineParkinsonism & Related Disorders
- 26 August 2019
Serum Uric Acid Level as a Biomarker in Idiopathic and Genetic (p.A53T Alpha-Synuclein Carriers) Parkinson's Disease: Data from the PPMI Study.
- C. Koros, A. Simitsi, L. Stefanis
- Biology, MedicineJournal of Parkinson's Disease
- 11 March 2020
This study did not replicate the established lower serum uric acid measurements in PD patients as compared to controls using PPMI data, possibly due to the fact that PD patients in baseline visit were de novo and the average disease duration was shorter than that observed in most epidemiological PD studies.
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