A. Shingleton

Publications64
h-index29
Citations3,360
Highly Influential Citations205
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A comparison of parthenogenetic and sexual embryogenesis of the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidoidea).
Aphids exhibit divergent modes of embryogenesis during the sexual and asexual phases of the life cycle. To explore how a single genome can give rise to these alternative developmental modes, we have… Expand
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The Temporal Requirements for Insulin Signaling During Development in Drosophila
Recent studies have indicated that the insulin-signaling pathway controls body and organ size in Drosophila, and most metazoans, by signaling nutritional conditions to the growing organs. The… Expand
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Size and shape: the developmental regulation of static allometry in insects
Among all organisms, the size of each body part or organ scales with overall body size, a phenomenon called allometry. The study of shape and form has attracted enormous interest from biologists, but… Expand
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Imaginal discs regulate developmental timing in Drosophila melanogaster.
The regulation of body size in animals involves mechanisms that terminate growth. In holometabolous insects growth ends at the onset of metamorphosis and is contingent on their reaching a critical… Expand
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Host plant and ants influence the honeydew sugar composition of aphids
Summary 1 Honeydew composition is an important factor in mediating ant–homopteran mutualisms. The trisaccharide melezitose is especially significant in this interaction. Honeydew of three… Expand
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FOXO Regulates Organ-Specific Phenotypic Plasticity In Drosophila
Phenotypic plasticity, the ability for a single genotype to generate different phenotypes in response to environmental conditions, is biologically ubiquitous, and yet almost nothing is known of the… Expand
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The developmental control of size in insects
The mechanisms that control the sizes of a body and its many parts remain among the great puzzles in developmental biology. Why do animals grow to a species‐specific body size, and how is the… Expand
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Nutritional control of body size through FoxO-Ultraspiracle mediated ecdysone biosynthesis
Despite their fundamental importance for body size regulation, the mechanisms that stop growth are poorly understood. In Drosophila melanogaster, growth ceases in response to a peak of the molting… Expand
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Integrating Body and Organ Size in Drosophila: Recent Advances and Outstanding Problems
Over the past two decades, fundamental strides in physiology and genetics have allowed us to finally grasp the developmental mechanisms regulating body size, primarily in one model organism: the… Expand
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Many ways to be small: different environmental regulators of size generate distinct scaling relationships in Drosophila melanogaster
Static allometries, the scaling relationship between body and trait size, describe the shape of animals in a population or species, and are generated in response to variation in genetic or… Expand
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