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Presentation and outcome of rhino-orbital-cerebral mucormycosis in patients with diabetes
TLDR
Ophthalmic and extensive cerebral involvement predominated in the clinical picture in patients with diabetes and ROCM, and delay in treatment due to late presentation and associated complications were major determinants of the survival outcome in these patients.
Pigmentary changes in chronic myeloid leukemia patients treated with imatinib mesylate.
TLDR
Treatment of HIV-associated multicentric Castleman’s disease with oral etoposide and the effect of protease inhibitor on clinical and virological evolution of Castleman's disease in an HIV-1 infected patient is revealed.
Colorectal cancers--experience at a regional cancer centre in India.
TLDR
A significant number of CRC patients in India present with advanced stage of disease and probably due to referral bias majority had low rectal cancers, so by advocating multimodality protocols a good locoregional and systemic control can be achieved despite theAdvanced stage of presentation.
Prevalence of ZAP-70 and CD 38 in Indian chronic lymphocytic leukemia patients.
TLDR
ZAP-70 and CD 38 positivity were detected 25% and 36%, respectively, with concordance rate of 56%, which is higher than Western literature, and there was no correlation of ZAP- 70 and CD 37 positivity with age, sex, lymphadenopathy, organomegaly, and Rai staging.
Inflammation: its role and interplay in the development of cancer, with special focus on gynecological malignancies
TLDR
The appreciation of the role of inflammation in carcinogenesis provides a mechanistic framework to understand clinical benefits of newer therapeutic strategies and help clinicians in better management of the disease.
Analysis of 2167 head and neck cancer patients' management, treatment compliance and outcomes from a regional cancer centre, Delhi, India
TLDR
Head and neck cancer care was analysed in 2167 unselected patients for management compliance and outcome and showed wide disparities in stage of presentation and survival.
Severe tumor lysis syndrome during treatment with STI 571 in a patient with chronic myelogenous leukemia accelerated phase.
Signal transduction inhibitor 571 (STI 571), a potent and selective inhibitor of the tyrosine kinase activity of BCR– ABL, is an important advance in the treatment of chronic myelogenous leukemia
Outcome of combined modality treatment including neoadjuvant chemotherapy of 128 cases of locally advanced breast cancer: data from a tertiary cancer center in northern India.
TLDR
This study analyzes the outcome in patients who received NACT, in the largest number of LABC patients from a single center in India, and the results are comparable to the results reported from other centers.
Concomitant chemoradiation versus radical radiotherapy in advanced squamous cell carcinoma of oropharynx and nasopharynx using weekly cisplatin: a phase II randomized trial.
TLDR
This trial on Indian head and neck squamous cell carcinoma patients confirms that the use of weekly cisplatin is safe and CRT is superior to RT alone resulting in higher OS.
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