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Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease
TLDR
Locally injected MSCs represent a feasible, safe and beneficial therapy in refractory fistulising Crohn's disease and have been proven to affect mucosal T cell apoptotic rate.
Long-Term Follow-Up of Crohn Disease Fistulas After Local Injections of Bone Marrow-Derived Mesenchymal Stem Cells.
TLDR
Locally injected MSCs constitute a safe therapy that rescues refractory patients and regains responsiveness to drugs previously proved ineffective in terms of safety and efficacy.
Trends in axillary lymph node dissection for early-stage breast cancer in Europe: Impact of evidence on practice.
TLDR
There was a decrease in rates of ALND that started after year 2010 through the end of the study period, indicating the need to spread unified clinical guidelines in Europe to allow for homogeneous evidence-based practice patterns.
Recurrence of Giant Juvenile Breast Fibroadenoma in a Girl with Turner's Syndrome
TLDR
A case of recurrent juvenile giant breast fibroadenoma in a girl with Turner's syndrome is reported, and local recurrence is unusual.
Low-Grade Fibromatosis-Like Spindle Cell Metaplastic Carcinoma: A Basal-Like Tumor with a Favorable Clinical Outcome. Report of Two Cases
TLDR
Although the biological behavior of this subtype of breast cancer has not been adequately evaluated, wide local excision or mastectomy with clear resection margins but no axillary dissection appears to be an adequate treatment approach.
Bortezomib-induced paralytic ileus is a potential gastrointestinal side effect of this first-in-class anticancer proteasome inhibitor.
TLDR
A myeloma patient is reported who developed severe paralytic ileus during bortezomib therapy, which presented in the context of progressive constipation without other known causes and which regressed promptly with medical management after drug cessation, suggesting a direct causal relationship.
99mTc-68Ga-ICG-Labelled Macroaggregates and Nanocolloids of Human Serum Albumin: Synthesis Procedures of a Trimodal Imaging Agent Using Commercial Kits
TLDR
A trimodal SLN/ROLL targeting agent (99mTc-68Ga-ICG) with commercially available kits of macroaggregated or nanocolloidal albumin (MA/NC-HSA) is studied to optimise the labelling and tagging of these two radiopharmaceuticals and assess their yields and stability.
Management of the axilla in patients with breast cancer and positive sentinel lymph node biopsy: An evidence-based update in a European breast center.
TLDR
It is determined that axillary dissection after a positive sentinel lymph node biopsy may be avoided in cN0 patients with micro/macrometastasis to ≤2 sentinel nodes, with age ≥40y, lesions ≤3 cm, who have not received neoadjuvant chemotherapy and have planned breast conservation with whole breast radiotherapy (WBRT).
La terapia per cattura neutronica (BNCT) dei tumori epatici diffusi: prima applicazione clinica
La forma anatomo-clinica di interessamento neoplastico del fegato di più frequente riscontro nella nostra area geografica è rappresentata da una neoplasia del grosso intestino con metastasi epatiche
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