A. Serafino

Publications113
h-index33
Citations2,728
Highly Influential Citations96
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The activation of human endogenous retrovirus K (HERV-K) is implicated in melanoma cell malignant transformation.
Melanoma development is a multi-step process arising from a series of genetic and epigenetic events. Although the sequential stages involved in progression from melanocytes to malignant melanoma are… Expand
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Inhibition of endogenous reverse transcriptase antagonizes human tumor growth
Undifferentiated cells and embryos express high levels of endogenous non-telomerase reverse transcriptase (RT) of retroposon/retroviral origin. We previously found that RT inhibitors modulate cell… Expand
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Roughness of the plasma membrane as an independent morphological parameter to study RBCs: a quantitative atomic force microscopy investigation.
A novel approach to the study of RBCs based on the collection of three-dimensional high-resolution AFM images and on the measure of the surface roughness of their plasma membrane is presented. The… Expand
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Gene expression profiling of human macrophages at late time of infection with Mycobacterium tuberculosis
Macrophages play an essential role in the immune response to Mycobacterium tuberculosis (Mtb). Previous transcriptome surveys, by means of micro‐ and macroarrays, investigated the cellular gene… Expand
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Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
BackgroundBesides few data concerning the antiseptic properties against a range of microbial agents and the anti-inflammatory potential both in vitro and in vivo, little is known about the influence… Expand
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Cytotoxicity and inflammatory potential of soot particles of low-emission diesel engines.
We evaluated, in vitro, the inflammatory and cytotoxic potential of soot particles from current low-emission (Euro IV) diesel engines toward human peripheral blood monocyte-derived macrophage cells.… Expand
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Bcl-2 Expression and p38MAPK Activity in Cells Infected with Influenza A Virus
Previous reports have shown that various steps in the influenza A virus life cycle are impaired in cells expressing the antiapoptotic protein Bcl-2 (Bcl-2+ cells). We demonstrated a direct link… Expand
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Differentiation of normal and cancer cells induced by sulfhydryl reduction: biochemical and molecular mechanisms
We examined the morphological, biochemical and molecular outcome of a nonspecific sulfhydryl reduction in cells, obtained by supplementation of N-acetyl-L-cysteine (NAC) in a 0.1–10 mM concentration… Expand
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Binding of Clostridium difficile to Caco-2 epithelial cell line and to extracellular matrix proteins.
Adhesion of Clostridium difficile to Caco-2 was examined as a function of monolayers polarization and differentiation. The number of adherent C. difficile C253 bacteria per cell strongly decreased… Expand
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Low electromagnetic field (50 Hz) induces differentiation on primary human oral keratinocytes (HOK).
This work concerns the effect of low frequency electromagnetic fields (ELF) on biochemical properties of human oral keratinocytes (HOK). Cells exposed to a 2 mT, 50 Hz, magnetic field, showed by… Expand
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