Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries.
The preliminary findings suggest that the abnormal vascular response to acetylcholine may represent a defect in endothelial vasodilator function, and may be important in the pathogenesis of coronary vasospasm.
The effect of atherosclerosis on the vasomotor response of coronary arteries to mental stress.
Atherosclerosis disturbs the normal vasomotor response (no change or dilation) of large coronary arteries to mental stress; in patients with atherosclerosis paradoxical constriction occurs during mental stress, particularly at points of stenosis.
Endocardial and epicardial radiofrequency ablation of ventricular tachycardia associated with dilated cardiomyopathy: the importance of low-voltage scars.
Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease.
In animals, acetylcholine dilates normal arteries and produces vasoconstriction in the presence of hypercholesterolemia, hypertension, or atherosclerosis, reflecting endothelial cell dysfunction. In…
Dilation of normal and constriction of atherosclerotic coronary arteries caused by the cold pressor test.
The response of normal coronary arteries to the CPT test is dilation, in part related to beta-adrenoreceptor stimulation and possibly flow-mediated endothelial dilation or alpha 2- adrenergic activity.
The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion.
- T. Anderson, I. Meredith, A. Yeung, B. Frei, A. Selwyn, P. Ganz
- MedicineNew England Journal of Medicine
- 23 February 1995
The improvement in endothelium-dependent vasomotion with cholesterol-lowering and antioxidant therapy may have important implications for the activity of myocardial ischemia and may explain in part the reduced incidence of adverse coronary events that is known to result from cholesterol- Lowering therapy.
Flow-induced vasodilation of the human brachial artery is impaired in patients <40 years of age with coronary artery disease.
Endothelium-Derived Nitric Oxide Regulates Arterial Elasticity in Human Arteries In Vivo
It is hypothesized that NO, a vasodilator released constitutively by the endothelium, augments arterial elasticity in the human brachial artery and may adversely affect arterial Elasticity in humans.
Estrogen Improves Endothelium-Dependent, Flow-Mediated Vasodilation in Postmenopausal Women
It is hypothesized that long-term estrogen administration would improve vasomotor function in postmenopausal women and was conducted in a double-blind, randomized, crossover, placebo-controlled trial.