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Microbial Production and Biomedical Applications of Lovastatin
The structure, biosynthesis, various modes of fermentation and applications of lovastatin, a potent hypercholesterolemic drug used for lowering blood cholesterol, are reviewed. Expand
Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS
It is shown that DTD’s active site architecture can efficiently edit mischarged Gly-tRNAAla species four orders of magnitude more efficiently than even AlaRS, the only ubiquitous cellular checkpoint known for clearing the error. Expand
Quantification of Lovastatin Produced by Monascus purpureus
Development of a novel method for the quantification of lovastatin is an interesting problem in the analytical field. In the literature, many reports use spectrophotometric method for theExpand
Lovastatin Nanoparticle Synthesis and Characterization for Better Drug Delivery
Nano drug delivery system is the latest technology employed in various medicinal applications. This technol- ogy can be adapted to the conventional drug administration due to its site-specificExpand
Metabolic pathway analysis and dynamic macroscopic model development for lovastatin production by Monascus purpureus using metabolic footprinting concept
Abstract Understanding and modeling of the metabolic pathway of a cell by probing the fraction of extracellular metabolites is gaining much interest in biological reactions. This communication dealsExpand
Characterization of Terephthalic Acid Monomer Recycled from Post-Consumer PET Polymer Bottles
Summary The idea of recycling of PET to obtain terephthalic acid (TPH) monomer is fast gaining traction; therefore it has become imperative to develop standard characterization methods to assessExpand
Characterization, Modes of Synthesis, and Pleiotropic Effects of Hypocholesterolemic Compounds – A Review
Major natural sources as well as synthetic and biological routes of synthesis of these compounds are reviewed in a concise manner and various HMG-CoA analogues including statins have been reviewed specifically. Expand
Comparison of the elution characteristics of individual forms of lovastatin in both isocratic and gradient modes and HPLC-PDA method development for pure and fermentation-derived lovastatin
The fermentation broth (pH not adjusted) extracted with ethyl acetate at a ratio of 1:1 (v/v) at 60°C for 30 min was the optimal extraction condition for lovastatin. Expand
Women Empowerment in Tamil Nadu Emerging Trends and State Initiatives By Mr .
Noncommercial 3.0 Unported License http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work isExpand