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Multiple high risk HPV infections are common in cervical neoplasia and young women in a cervical screening population
Aims: If human papillomavirus (HPV) testing is to be included within cervical screening programmes, the importance of multiple HPV infections in cervical neoplasia needs to be determined. This studyExpand
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Human and Animal Infections with Mycobacterium microti, Scotland
During 1994–2005, we isolated Mycobacterium microti from 5 animals and 4 humans. Only 1 person was immunocompromised. Spoligotyping showed 3 patterns: vole type, llama type, and a new variant llamaExpand
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Rapid real time PCR to distinguish between high risk human papillomavirus types 16 and 18
Aims—To assess the validity and practicality of real time polymerase chain reaction (PCR) for human papillomavirus (HPV) testing in combination with liquid based cytology samples for cervicalExpand
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Three year evaluation of Xpert MTB/RIF in a low prevalence tuberculosis setting: A Scottish perspective.
OBJECTIVES Xpert MTB/RIF (Cepheid) is a rapid molecular assay shown to be sensitive and specific for pulmonary tuberculosis (TB) diagnosis in highly endemic countries. We evaluated its diagnosticExpand
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A longitudinal study of HPV detection and cervical pathology in HIV infected women
Objective: To monitor the presence and persistence of high risk (HR) human papillomavirus (HPV) in cervical brushings from HIV infected women. Methods: Prospective observational cohort study of HIVExpand
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Investigating Transmission of Mycobacterium bovis in the United Kingdom in 2005 to 2008
ABSTRACT Due to an increase in bovine tuberculosis in cattle in the United Kingdom, we investigated the characteristics of Mycobacterium bovis infection in humans and assessed whether extensiveExpand
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Molecular Longitudinal Tracking of Mycobacterium abscessus spp. during Chronic Infection of the Human Lung
The Mycobacterium abscessus complex is an emerging cause of chronic pulmonary infection in patients with underlying lung disease. The M. abscessus complex is regarded as an environmental pathogen butExpand
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Evaluation of the GenoType Mycobacteria Direct assay for the simultaneous detection of the Mycobacterium tuberculosis complex and four atypical mycobacterial species in smear-positive respiratory
A novel, commercially available reverse hybridization assay [GenoType Mycobacteria Direct (GTMD), version 2.0; Hain Lifescience] was evaluated for the direct detection of five clinically relevantExpand
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Rapid real-time PCR for detection of Mycobacterium tuberculosis complex DNA in formalin-fixed paraffin embedded tissues: 16% of histological ‘sarcoid’ may contain such DNA
Aims To investigate the diagnostic accuracy of IS6110 real-time PCR for detection of Mycobacterium tuberculosis complex (MTBC) in DNA extracted from formalin-fixed paraffin embedded (FFPE) tissuesExpand
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Characterising transmission of a tuberculosis genotype in Scotland: a qualitative approach to social network enquiry.
SETTING Contact investigation resulting from specimens sent to the Scottish Mycobacteria Reference Laboratory. OBJECTIVE To characterise patients and types of exposures associated with transmissionExpand
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