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Endocytic membrane trafficking and neurodegenerative disease
Neurodegenerative diseases are amongst the most devastating of human disorders. New technologies have led to a rapid increase in the identification of disease-related genes with an enhancedExpand
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LRRK2 localizes to endosomes and interacts with clathrin‐light chains to limit Rac1 activation
Mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common cause of dominant‐inherited Parkinson's disease (PD), and yet we do not fully understand the physiological function(s) of LRRK2.Expand
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Hormesis and Cellular Quality Control: A Possible Explanation for the Molecular Mechanisms that Underlie the Benefits of Mild Stress
In contrast to the detrimental action of severe stress conditions, the beneficial effects of mild stress, known as hormesis, is increasingly discussed and studied. A variety of applications forExpand
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LRRK 2 localizes to endosomes and interacts with clathrin-light chains to limit Rac 1 activation
As the reports are below, I will not detail them here. However, the study would clearly need to be substantially strengthened regarding its functional and physiological relevance (such as assayingExpand
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Social capital among smallholder farmers in Samia District, Kenya
Social capital can be an important poverty reduction tool in smallholder farming communities. People may turn to friends, kin or community members for assistance in times of hardship and need. PeopleExpand
Livelihoods and vulnerability of smallholder farmers in Samia District, Kenya
In many sub-Saharan African countries smallholder farmers are vulnerable to food and income insecurity. Population growth, pressure on land, climatic change, and migration affect agriculturalExpand