• Publications
  • Influence
Composition of symbiotic bacteria predicts survival in Panamanian golden frogs infected with a lethal fungus
Symbiotic microbes can dramatically impact host health and fitness, and recent research in a diversity of systems suggests that different symbiont community structures may result in distinct outcomesExpand
  • 92
  • 14
  • PDF
Fighting a Losing Battle: Vigorous Immune Response Countered by Pathogen Suppression of Host Defenses in the Chytridiomycosis-Susceptible Frog Atelopus zeteki
The emergence of the disease chytridiomycosis caused by the chytrid fungus Batrachochytrium dendrobatidis (Bd) has been implicated in dramatic global amphibian declines. Although many species haveExpand
  • 83
  • 9
  • PDF
Seasonal and ontogenetic variation of skin microbial communities and relationships to natural disease dynamics in declining amphibians
Recently, microbiologists have focused on characterizing the probiotic role of skin bacteria for amphibians threatened by the fungal disease chytridiomycosis. However, the specific characteristics ofExpand
  • 80
  • 9
  • PDF
Genetic diversity of MHC class I loci in six non-model frogs is shaped by positive selection and gene duplication
Comparative studies of major histocompatibility complex (MHC) genes across vertebrate species can reveal the evolutionary processes that shape the structure and function of immune regulatoryExpand
  • 34
  • 9
  • PDF
MHC genotypes associate with resistance to a frog-killing fungus
  • A. Savage, K. Zamudio
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 26 September 2011
The emerging amphibian disease chytridiomycosis is caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd). Amphibian populations and species differ in susceptibility to Bd, yet we knowExpand
  • 270
  • 7
  • PDF
Adaptive tolerance to a pathogenic fungus drives major histocompatibility complex evolution in natural amphibian populations
  • A. Savage, K. Zamudio
  • Biology, Medicine
  • Proceedings of the Royal Society B: Biological…
  • 30 March 2016
Amphibians have been affected globally by the disease chytridiomycosis, caused by the fungus Batrachochytrium dendrobatidis (Bd), and we are just now beginning to understand how immunogeneticExpand
  • 76
  • 7
  • PDF
Toward Immunogenetic Studies of Amphibian Chytridiomycosis: Linking Innate and Acquired Immunity
Recent declines in amphibian diversity and abundance have contributed significantly to the global loss of biodiversity. The fungal disease chytridiomycosis is widely considered to be a primary causeExpand
  • 88
  • 6
  • PDF
Gametophytic self-incompatibility in Lycium parishii (Solanaceae): allelic diversity, genealogical structure, and patterns of molecular evolution at the S-RNase locus
We characterized allelic diversity at the locus controlling self-incompatibility (SI) for a population of Lycium parishii (Solanaceae) from Organ Pipe National Monument, Arizona. Twenty-four partialExpand
  • 30
  • 5
  • PDF
Linking genetic and environmental factors in amphibian disease risk
A central question in evolutionary biology is how interactions between organisms and the environment shape genetic differentiation. The pathogen Batrachochytrium dendrobatidis (Bd) has causedExpand
  • 49
  • 4
  • PDF
First Record of Batrachochytrium dendrobatidis Infecting Four Frog Families from Peninsular Malaysia
The fungal pathogen Batrachochytrium dendrobatidis (Bd) infects amphibians on every continent where they occur and is linked to the decline of over 200 amphibian species worldwide. At present, onlyExpand
  • 25
  • 4
  • PDF
...
1
2
3
4
5
...