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Seroprevalence of herpes simplex virus type 1 and type 2 in selected German populations—relevance for the incidence of genital herpes
This study was carried out to determine the prevalence of antibodies to herpes simplex virus types 1 (HSV‐1) and 2 (HSV‐2) in selected German populations, such as blood donors, hospital patients, and… Expand
Laboratory diagnosis of herpes zoster.
- A. Sauerbrei, U. Eichhorn, M. Schacke, P. Wutzler
- Journal of clinical virology : the official…
- 1 September 1999
Virological diagnosis of zoster should be rapid when effective antiviral chemotherapy is being considered. In the present study, vesicle specimens of 100 patients with zoster were analysed by… Expand
Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus.
Sixteen herpes simplex virus type 1 (HSV-1) and four type 2 (HSV-2) isolates resistant to acyclovir (ACV) were characterized retrospectively for drug resistance. Phenotypic testing was performed by… Expand
Laboratory diagnosis of central nervous system infections caused by herpesviruses.
BACKGROUND Herpesviruses may be associated with various types of central nervous system (CNS) infections. Herpes simplex encephalitis (HSE) has to be considered one of the most severe diseases. As… Expand
Evolution and world-wide distribution of varicella-zoster virus clades.
- J. Schmidt-Chanasit, A. Sauerbrei
- Biology, Medicine
- Infection, genetics and evolution : journal of…
Varicella-zoster virus (VZV, Human herpesvirus 3), a world-wide distributed pathogen, is the causative agent of varicella (chickenpox) and zoster (shingles). Both diseases result in significant… Expand
Herpes simplex and varicella-zoster virus infections during pregnancy: current concepts of prevention, diagnosis and therapy. Part 2: Varicella-zoster virus infections
Varicella during pregnancy can be associated with severe illnesses for both the mother and her neonate. Varicella pneumonia must be regarded as a medical emergency, since pregnant women are at risk… Expand
Distribution of varicella-zoster virus (VZV) wild-type genotypes in northern and southern Europe: evidence for high conservation of circulating genotypes.
Phylogenetic analysis of 19 complete VZV genomic sequences resolves wild-type strains into 5 genotypes (E1, E2, J, M1, and M2). Complete sequences for M3 and M4 strains are unavailable, but targeted… Expand
Testing thermal resistance of viruses
Representative viral strains recommended for virucidal testing of biocides in human medicine were used for testing viral resistance to dry heat using the new Keredusy hot instrument. The results… Expand
Diagnosis, antiviral therapy, and prophylaxis of varicella-zoster virus infections
- A. Sauerbrei
- European Journal of Clinical Microbiology…
- 12 February 2016
Varicella-zoster virus (VZV), an important member of the Herpesviridae family, is the etiological agent of varicella as primary infection and zoster as recurrence. An outstanding feature is the… Expand
Seroprevalence of hepatitis E virus (HEV) in humans living in high pig density areas of Germany
- A. Krumbholz, S. Joel, +11 authors R. Zell
- Medicine, Biology
- Medical Microbiology and Immunology
- 18 April 2014
Abstract An increase in acute autochthonous hepatitis E virus (HEV) infections has been recorded in Germany. These are suspected to be zoonotically transmitted from wild boar, deer and domestic pig.… Expand